Association of Apremilast With Vascular Inflammation and Cardiometabolic Function in Patients With Psoriasis: The VIP-A Phase 4, Open-label, Nonrandomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2022.3862
Abstract: Importance Psoriasis is an inflammatory condition associated with metabolic and cardiovascular disease. Apremilast, a phosphodiesterase 4 inhibitor, is commonly used for psoriasis and can cause weight loss. Objective To determine the association between apremilast and… read more here.
Keywords: vascular inflammation; nonrandomized clinical; trial; dermatology ... See more keywords
Complement C5a‐triggered differentiated HL‐60 stimulates migration of THP‐1 monocytic leukocytes via secretion of CCL2
Sign Up to like & getrecommendations! Published in 2021 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13144
Abstract: Leukocytes play an important role in vascular inflammation prior to atherosclerosis. In particular, monocyte adhesion and migration to the endothelium contribute to the development of vascular inflammation. Previously, we showed the importance of neutrophils and… read more here.
Keywords: secretion; migration thp; ccl2; complement c5a ... See more keywords
Effects of soy isoflavones on serum systemic and vascular inflammation markers and oxidative stress in peritoneal dialysis patients: A randomized controlled trial
Sign Up to like & getrecommendations! Published in 2020 at "Phytotherapy Research"
DOI: 10.1002/ptr.6729
Abstract: Cardiovascular disease (CVD) is common in peritoneal dialysis (PD) patients. This study was designed to investigate the effects of isoflavones on systemic and vascular inflammation markers and oxidative stress in PD patients. In this randomized… read more here.
Keywords: systemic vascular; group; peritoneal dialysis; placebo group ... See more keywords
Updates in the Impact of Chronic Systemic Inflammation on Vascular Inflammation by Positron Emission Tomography (PET)
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DOI: 10.1007/s11886-022-01651-2
Abstract: In this review, we focus on the clinical and epidemiological studies pertaining to systemic and vascular inflammation by positron emission tomography (PET) in patients with chronic inflammatory conditions such as rheumatoid arthritis (RA), systemic lupus… read more here.
Keywords: vascular inflammation; systemic inflammation; inflammation positron; chronic systemic ... See more keywords
Omega-3 fatty acids ameliorate vascular inflammation: A rationale for their atheroprotective effects.
Sign Up to like & getrecommendations! Published in 2021 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2021.03.003
Abstract: BACKGROUND AND AIMS Clinical trials have demonstrated reductions in major adverse cardiovascular events with purified high-dose eicosapentaenoic acid (EPA), independent of effects on lipids. We aimed to investigate whether omega-3 fatty acids reduce vascular inflammation,… read more here.
Keywords: epa dha; fatty acids; inflammation; omega fatty ... See more keywords
The relationship between duration of psoriasis, vascular inflammation, and cardiovascular events
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2017.06.028
Abstract: Background: Psoriasis is associated with risk of cardiovascular (CV) disease (CVD) and a major adverse CV event (MACE). Whether psoriasis duration affects risk of vascular inflammation and MACEs has not been well characterized. Objectives: We… read more here.
Keywords: risk; psoriasis duration; duration; psoriasis ... See more keywords
Nepeta angustifolia attenuates responses to vascular inflammation in high glucose-induced human umbilical vein endothelial cells through heme oxygenase-1 induction.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2018.11.015
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE The traditional folk medicine Nepeta angustifolia C. Y. Wu (NA) reportedly possesses various biological activities, such as anti-inflammatory, analgesic, antihypoxia, and antifatigue effects. In this study, we evaluated the anti-vascular inflammation effects of… read more here.
Keywords: inflammation; human umbilical; high glucose; nepeta angustifolia ... See more keywords
Regulation of endothelial intracellular adenosine via adenosine kinase epigenetically modulates vascular inflammation
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DOI: 10.1038/s41467-017-00986-7
Abstract: The molecular mechanisms underlying vascular inflammation and associated inflammatory vascular diseases are not well defined. Here we show that endothelial intracellular adenosine and its key regulator adenosine kinase (ADK) play important roles in vascular inflammation.… read more here.
Keywords: adenosine kinase; vascular inflammation; inflammation; intracellular adenosine ... See more keywords
High intraluminal pressure promotes vascular inflammation via caveolin-1
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DOI: 10.1038/s41598-021-85476-z
Abstract: The aetiology and progression of hypertension involves various endogenous systems, such as the renin angiotensin system, the sympathetic nervous system, and endothelial dysfunction. Recent data suggest that vascular inflammation may also play a key role… read more here.
Keywords: intraluminal pressure; high intraluminal; caveolin; vascular inflammation ... See more keywords
CFTR protects against vascular inflammation and atherogenesis in apolipoprotein E-deficient mice
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DOI: 10.1042/bsr20170680
Abstract: Atherosclerosis is a chronic inflammatory disease of the vascular wall. Dysfunction of cystic fibrosis transmembrane conductance regulator (CFTR) has been shown to result in inflammatory responses in cystic fibrosis (CF) patients. However, little is known… read more here.
Keywords: cftr; inflammation atherogenesis; vascular inflammation; mice ... See more keywords
Crataegus Aronia protects and reverses vascular inflammation in a high fat diet rat model by an antioxidant mechanism and modulating serum levels of oxidized low-density lipoprotein
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceutical Biology"
DOI: 10.1080/13880209.2018.1564930
Abstract: Abstract Context: Crataegus aronia (Willd.) Bosc (Rosaceae) (syn. Azarolus L) is traditionally used to treat cardiovascular disorders. Objectives: To investigate C. aronia protection against a high-fat diet (HFD)-induced vascular inflammation in rats. Materials and methods:… read more here.
Keywords: fat diet; crataegus aronia; aronia; high fat ... See more keywords