MicroRNA-939 governs vascular integrity and angiogenesis through targeting γ-catenin in endothelial cells.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.01.085
Abstract: Coronary collateral circulation (CCC) functions as a natural bypass in the event of coronary obstruction, which markedly improves prognosis in patients with coronary artery disease (CAD). MicroRNAs (miRNAs) have been implicated in multiple physiological and… read more here.
Keywords: targeting catenin; angiogenesis; mir 939; vascular integrity ... See more keywords
Mechanosensitive TRPV4 channels stabilize VE-cadherin junctions to regulate tumor vascular integrity and metastasis.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer letters"
DOI: 10.1016/j.canlet.2018.07.042
Abstract: The transient receptor potential vanilloid 4 (TRPV4) channel is a mechanosensor in endothelial cells (EC) that regulates cyclic strain-induced reorientation and flow-mediated nitric oxide production. We have recently demonstrated that TRPV4 expression is reduced in… read more here.
Keywords: tumor vascular; vascular integrity; metastasis; cell ... See more keywords
Role of hedgehog signaling in developmental vascular integrity
Sign Up to like & getrecommendations! Published in 2017 at "Mechanisms of Development"
DOI: 10.1016/j.mod.2017.04.101
Abstract: The Primary Cilium (PC) is an important signalling platform of the cell. Previous studies revealed that PC are present on endothelial cells but their function in the vasculature remains under-explored. Kallakuri et al (2015) showed… read more here.
Keywords: ich; vascular integrity; pathway; role ... See more keywords
Macrophagic Stabilin-1 Restored Disruption of Vascular Integrity Caused by Sepsis.
Sign Up to like & getrecommendations! Published in 2018 at "Thrombosis and haemostasis"
DOI: 10.1055/s-0038-1669477
Abstract: Sepsis develops because of overwhelming inflammatory responses to bacterial infection, and disrupts vascular integrity. Stabilin-1 (STAB-1) is a phagocytic receptor, which mediates efferocytosis in a phosphatidylserine (PS)-dependent manner. STAB-1 is expected to play important roles… read more here.
Keywords: sepsis; stabilin; stab; vascular integrity ... See more keywords
The effect of Salix alba L. bark extract on dark circles in vitro and in vivo.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of cosmetic science"
DOI: 10.1111/ics.12873
Abstract: OBJECTIVE Dark circles in the infraorbital area are a common cosmetic concern among individuals because they exhibit fatigue and are undesirable across all ages. Of the dark circle etiologies, blood stasis by poor vascular integrity… read more here.
Keywords: dark circles; sabe; effect; salix alba ... See more keywords
New connections: Multiple paths control vascular integrity
Sign Up to like & getrecommendations! Published in 2017 at "Science Signaling"
DOI: 10.1126/scisignal.aam8349
Abstract: A pair of studies identifies new targets to prevent pathological vascular permeability. A pair of studies identifies new targets to prevent pathological vascular permeability. read more here.
Keywords: paths control; vascular integrity; connections multiple; new connections ... See more keywords
Resident macrophages restrain pathological adipose tissue remodeling and protect vascular integrity in obese mice
Sign Up to like & getrecommendations! Published in 2021 at "EMBO Reports"
DOI: 10.15252/embr.202152835
Abstract: Tissue‐resident macrophages in white adipose tissue (WAT) dynamically adapt to the metabolic changes of their microenvironment that are often induced by excess energy intake. Currently, the exact contribution of these macrophages in obesity‐driven WAT remodeling… read more here.
Keywords: wat; vascular integrity; tissue; adipose tissue ... See more keywords
Vascular Integrity and Signaling Determining Brain Development, Network Excitability, and Epileptogenesis
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2019.01583
Abstract: Our understanding of the etiological mechanisms leading up to epilepsy has undergone radical changes over time due to more insights into the complexity of the disease. The traditional hypothesis emphasized network hyperexcitability and an imbalance… read more here.
Keywords: epilepsy; integrity signaling; network; vascular integrity ... See more keywords
Autophagic degradation of LOX-1 is involved in the maintenance of vascular integrity injured by oxLDL and protected by Berberine
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.80958
Abstract: Damage to vascular endothelial cells (VECs) and vascular smooth muscle cells (VSMCs) caused by oxidized low-density lipoprotein (oxLDL) contributes to cardiovascular and cerebrovascular diseases. Protection effects of Berberine (BBR) on the cardiovascular system have been… read more here.
Keywords: vascular integrity; hcf; degradation lox;