Molecular Determinants of Tissue Specificity of Flavivirus Nonstructural Protein 1 Interaction with Endothelial Cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.00661-22
Abstract: Flavivirus NS1 is secreted into the bloodstream from infected cells during a viral infection. Dengue virus NS1 contributes to severe dengue pathology such as endothelial dysfunction and vascular leak independently of the virus. ABSTRACT Members… read more here.
Keywords: endothelial cells; pathology; flavivirus ns1; vascular leak ... See more keywords
High circulating angiopoietin-2 levels exacerbate pulmonary inflammation but not vascular leak or mortality in endotoxin-induced lung injury in mice
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DOI: 10.1136/thoraxjnl-2017-210413
Abstract: Background Elevated plasma levels of angiopoietin-2 (ANGPT2) have been reported in patients with acute lung injury (ALI); however, it remains unclear whether this increase contributes to, or just marks, the underlying vasculopathic inflammation and leak… read more here.
Keywords: endotoxin induced; vascular leak; leak; mice ... See more keywords
A novel Vascular Leak Index identifies sepsis patients with a higher risk for in-hospital death and fluid accumulation
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DOI: 10.1186/s13054-022-03968-4
Abstract: Purpose Sepsis is a leading cause of morbidity and mortality worldwide and is characterized by vascular leak. Treatment for sepsis, specifically intravenous fluids, may worsen deterioration in the context of vascular leak. We therefore sought… read more here.
Keywords: sepsis; hospital death; death fluid; vascular leak ... See more keywords
Vascular Leaking, a Pivotal and Early Pathogenetic Event in Systemic Sclerosis: Should the Door Be Closed?
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DOI: 10.3389/fimmu.2018.02045
Abstract: The early phase of systemic sclerosis (SSc) presents edema as one of the main features: this is clinically evident in the digital swelling (puffy fingers) as well as in the edematous skin infiltration of the… read more here.
Keywords: sclerosis; pivotal early; vascular leak; leaking pivotal ... See more keywords