Categorical and/or continuous? Learning from vascular surgery
Sign Up to like & getrecommendations! Published in 2018 at "World Psychiatry"
DOI: 10.1002/wps.20565
Abstract: R. Krueger and his impressive international team of co-authors offer a clear and comprehensive review of current issues in dimensional approaches to classifying psychopathology. They make a challenging case for the advantages of this approach,… read more here.
Keywords: progress; vascular pathology; pathology; vascular surgery ... See more keywords
Predictive variables for the presence of vascular malformations as the cause of basal ganglia hemorrhages
Sign Up to like & getrecommendations! Published in 2018 at "Neurosurgical Review"
DOI: 10.1007/s10143-018-1040-3
Abstract: To evaluate potential bleeding sources and predictive variables for basal ganglia hemorrhage. Fifty-seven patients with basal ganglia hemorrhage admitted to our neurosurgical ICU between 2005 and 2016 were retrospectively reviewed. Univariate and multivariate logistic analyses… read more here.
Keywords: vascular pathology; predictive variables; hemorrhage; pathology ... See more keywords
A New Scoring System for Prediction of Underlying Vascular Pathology in Patients with Intracerebral Hemorrhage: The Modified Secondary Intracerebral Hemorrhage Score (mSICH).
Sign Up to like & getrecommendations! Published in 2020 at "World neurosurgery"
DOI: 10.1016/j.wneu.2020.06.139
Abstract: BACKGROUND Secondary intracerebral hemorrhage (SICH) score is used to predict risk of intracranial hemorrhage (ICH) associated vascular lesions. However, it has low clinical utility in identifying patients without need for neurovascular imaging. OBJECTIVE This study… read more here.
Keywords: intracerebral hemorrhage; vascular pathology; pathology; underlying vascular ... See more keywords
Therapeutic treatment with the anti-inflammatory drug candidate MW151 may partially reduce memory impairment and normalizes hippocampal metabolic markers in a mouse model of comorbid amyloid and vascular pathology
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0262474
Abstract: Alzheimer’s disease (AD) is the leading cause of dementia in the elderly, but therapeutic options are lacking. Despite long being able to effectively treat the ill-effects of pathology present in various rodent models of AD,… read more here.
Keywords: comorbid; mouse model; pathology; anti inflammatory ... See more keywords
Clinical criteria to exclude acute vascular pathology on CT angiogram in patients with dizziness
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0280752
Abstract: Background Patients presenting to the emergency department (ED) with dizziness may be imaged via CTA head and neck to detect acute vascular pathology including large vessel occlusion. We identify commonly documented clinical variables which could… read more here.
Keywords: rule; dizziness; acute vascular; pathology ... See more keywords
Sustained Upregulation of Endothelial Nox4 Mediates Retinal Vascular Pathology in Type 1 Diabetes.
Sign Up to like & getrecommendations! Published in 2022 at "Diabetes"
DOI: 10.2337/db22-0194
Abstract: NADPH oxidase 4 (Nox4) is a major source of reactive oxygen species (ROS) in retinal endothelial cells (ECs) and is upregulated under hyperglycemic and hypoxic conditions. However, the role of endothelial Nox4 upregulation in long-term… read more here.
Keywords: vascular pathology; retinal vascular; pathology; endothelial nox4 ... See more keywords
Diabetic rats with high levels of endogenous dopamine do not show retinal vascular pathology
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2023.1125784
Abstract: Purpose Limited research exists on the time course of long-term retinal and cerebral deficits in diabetic rodents. Previously, we examined short term (4–8 weeks) deficits in the Goto-Kakizaki (GK) rat model of Type II diabetes.… read more here.
Keywords: function; diabetic rats; dopamine; retinal vascular ... See more keywords