Deletion of DGCR8 in VSMCs of adult mice results in loss of vascular reactivity, reduced blood pressure and neointima formation
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-19660-z
Abstract: DiGeorge syndrome chromosomal region 8 (DGCR8), a double-stranded-RNA-binding protein, participates in the miRNA biogenesis pathway and contributes to miRNA maturation by interacting with the RNAase III enzyme Drosha in cell nuclei. To investigate the role… read more here.
Keywords: dgcr8; mice; vascular reactivity; blood pressure ... See more keywords
Effects of Δ9-Tetrahydrocannabinol and the Aminoalkylindole K2/Spice Constituent JWH-073 on Cardiac Tissue and Mesenteric Vascular Reactivity.
Sign Up to like & getrecommendations! Published in 2023 at "Cannabis and cannabinoid research"
DOI: 10.1089/can.2022.0325
Abstract: Background: Although use of Cannabis sativa is not associated with serious adverse effects, recreational use of aminoalkylindole (AAI) cannabinoid receptor agonists found in K2/Spice herbal blends has been reported to cause adverse cardiovascular events, including… read more here.
Keywords: mesenteric vascular; vascular reactivity; jwh; 073 thc ... See more keywords
Organ-specific changes in vascular reactivity and roles of inducible nitric oxide synthase and endothelin-1 in a rabbit endotoxic shock model
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Trauma and Acute Care Surgery"
DOI: 10.1097/ta.0000000000002036
Abstract: BACKGROUND Hemorrhagic shock-induced changes in vascular reactivity appear organ-specific. In the present study, we examined the hypothesis that vascular reactivity induced by septic shock similarly displays organ-specific differences and is regulated by inducible nitric oxide… read more here.
Keywords: organ specific; changes vascular; vascular reactivity; reactivity ... See more keywords
Chronic intermittent hypobaric hypoxia ameliorates vascular reactivity through upregulating adiponectin expression of PVAT in metabolic syndrome rats.
Sign Up to like & getrecommendations! Published in 2023 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2022-0252
Abstract: Cumulating evidence demonstrated that chronic intermittent hypobaric hypoxia (CIHH) had beneficial effects on the body. The present study investigated the role of perivascular adipose tissue (PVAT) in ameliorating effect of CIHH on vascular reactivity by… read more here.
Keywords: chronic intermittent; vascular reactivity; intermittent hypobaric; expression ... See more keywords
Pannexin 1 channels control CaV1.2 channel activity and vascular reactivity in diabetic hyperglycemia
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5731650
Abstract: Vascular complications are major causes of morbidity and mortality in diabetic patients. Recently, our group identified a novel purinergic signaling pathway involving the AKAP5/P2Y11/AC5/PKA/CaV1.2 protein network in arterial myocytes that is activated upon diabetic hyperglycemia… read more here.
Keywords: vascular reactivity; diabetic hyperglycemia; arterial myocytes; activity vascular ... See more keywords
Topical administration of Metamizole and its implications on vascular reactivity in Wistar rats- Experimental research
Sign Up to like & getrecommendations! Published in 2017 at "Romanian Journal of Ophthalmology"
DOI: 10.22336/rjo.2017.6
Abstract: Aim: The aim of this paper was to describe the possible implications of topical (ocular) administration of Metamizole on vascular reactivity of the iris in Wistar rats. No other study regarding its topical use was… read more here.
Keywords: wistar rats; metamizole; administration metamizole; vascular reactivity ... See more keywords
Chronic Low-Level Lead Exposure Increases Mesenteric Vascular Reactivity: Role of Cyclooxygenase-2-Derived Prostanoids
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2020.590308
Abstract: Lead (Pb) exposure causes hazardous effects as hypertension and other cardiovascular diseases. We evaluated whether chronic Pb exposure alters the peripheral vascular resistance measuring the vascular reactivity of mesenteric resistance arteries in rats to identify… read more here.
Keywords: cyclooxygenase; exposure; vascular reactivity; lead exposure ... See more keywords