Biomimetic Design of Artificial Hybrid Nanocells for Boosted Vascular Regeneration in Ischemic Tissues.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced materials"
DOI: 10.1002/adma.202110352
Abstract: Restoration of sufficient blood supply for the treatment of ischemia remains a significant scientific and clinical challenge. Here, we introduce a cell-like nanoparticle delivery technology that is capable of recapitulating multiple cell functions for the… read more here.
Keywords: artificial hybrid; ischemic tissues; cell; vascular regeneration ... See more keywords
MicroRNA‐212 promotes the recovery function and vascular regeneration of endothelial progenitor cells in mice with ischemic stroke through inactivation of the notch signaling pathway via downregulating MMP9 expression
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27463
Abstract: Ischemic stroke is a refractory disease caused by cerebral ischemic injury, which results in brain dysfunction. This study intends to investigate the effects of microRNA‐212 (miR‐212) on the recovery function and vascular regeneration of endothelial… read more here.
Keywords: ischemic stroke; vascular regeneration; mmp9; recovery function ... See more keywords
Human ESC-derived vascular cells promote vascular regeneration in a HIF-1α dependent manner.
Sign Up to like & getrecommendations! Published in 2023 at "Protein & cell"
DOI: 10.1093/procel/pwad027
Abstract: Hypoxia-inducible factor (HIF-1α), a core transcription factor responding to changes in cellular oxygen levels, is closely associated with a wide range of physiological and pathological conditions. However, its differential impacts on vascular cells types and… read more here.
Keywords: regeneration; cell; vascular cells; human esc ... See more keywords
Mesenchymal stem cells and vascular regeneration
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DOI: 10.1111/micc.12324
Abstract: In recent years, MSCs have emerged as a promising therapeutic cell type in regenerative medicine. They hold great promise for treating cardiovascular diseases, such as myocardial infarction and limb ischemia. MSCs may be utilized in… read more here.
Keywords: vascular regeneration; cell; regeneration; mesenchymal stem ... See more keywords
Autologous Cell Therapy for Vascular Regeneration: The Role of Proangiogenic Cells.
Sign Up to like & getrecommendations! Published in 2018 at "Current medicinal chemistry"
DOI: 10.2174/0929867324666171012111603
Abstract: BACKGROUND Autologous cell therapy represents a novel treatment option for vascular regeneration in different disease conditions, with experimental and clinical studies indicating a therapeutic potential for proangiogenic cells (PCs), including endothelial progenitor cells, in the… read more here.
Keywords: therapy; cell therapy; vascular regeneration; role ... See more keywords
Targeted delivery of nanomedicines for promoting vascular regeneration in ischemic diseases
Sign Up to like & getrecommendations! Published in 2022 at "Theranostics"
DOI: 10.7150/thno.73421
Abstract: Ischemic diseases, the leading cause of disability and death, are caused by the restriction or blockage of blood flow in specific tissues, including ischemic cardiac, ischemic cerebrovascular and ischemic peripheral vascular diseases. The regeneration of… read more here.
Keywords: ischemic diseases; vascular regeneration; delivery; delivery nanomedicines ... See more keywords