Missing self triggers NK cell-mediated chronic vascular rejection of solid organ transplants
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-13113-5
Abstract: Current doctrine is that microvascular inflammation (MVI) triggered by a transplant -recipient antibody response against alloantigens (antibody-mediated rejection) is the main cause of graft failure. Here, we show that histological lesions are not mediated by… read more here.
Keywords: chronic vascular; graft; rejection; vascular rejection ... See more keywords
Clinical and Pathological Analyses of Cases of Acute Vascular Rejection After Kidney Transplantation
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DOI: 10.1097/01.tp.0000543299.12925.21
Abstract: Aim We performed a clinical and pathological analysis of cases of acute vascular rejection (AVR), characterized by intimal arteritis and transmural arteritis (Banff ‘v’ score) after kidney transplantation, in an attempt to clarify the mechanisms… read more here.
Keywords: rejection; acute vascular; transplantation; cases acute ... See more keywords
The number of donor HLA-derived T cell epitopes available for indirect antigen presentation determines the risk for vascular rejection after kidney transplantation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.973968
Abstract: The role of the indirect T-cell recognition pathway of allorecognition in acute T cell-mediated rejection (aTCMR) is not well defined. The amount of theoretical T-cell epitopes available for indirect allorecognition can be quantified for donor-recipient… read more here.
Keywords: cell; hla; vascular rejection; donor ... See more keywords