SMOKING-RELATED ACCELERATED VASCULAR SENESCENCE IS REVERSED AFTER MORE THAN 15 YEARS OF QUITTING SMOKE
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000573728.02476.23
Abstract: S. Fontana1, L. Zagato1, R. Bigazzi2, C. Lanzani1, E. Messaggio1, G. Santini2, F. Nistri2, S. Delli Carpini1, L. Citterio1, M. Simonini1, S. Tentori1, E. Brioni1, C. Magnaghi1, S. Lenti3, S. Bianchi2, V. Campese4, M. P.… read more here.
Keywords: vascular senescence; smoking related; related accelerated; senescence reversed ... See more keywords
PCAF Accelerates Vascular Senescence via the Hippo Signaling Pathway
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DOI: 10.1155/2022/1200602
Abstract: P300/CBP-Associated Factor (PCAF), one of the histone acetyltransferases (HATs), is known to be involved in cell growth and/or differentiation. PCAF is reported to be involved in atherosclerotic plaques and neointimal formation. However, its role in… read more here.
Keywords: vascular senescence; signaling pathway; pcaf; senescence ... See more keywords
Association of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 With Angiotensin II Type 1 Receptor Impacts Mitochondrial Quality Control, Offering Promise for the Treatment of Vascular Senescence
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2021.788655
Abstract: Lectin-like oxidized low-density lipoprotein (ox-LDL) causes vascular senescence and atherosclerosis. It has been reported that ox-LDL scavenger receptor-1 (LOX-1) is associated with the angiotensin II type 1 receptor (AT1R). While mitochondria play a crucial role… read more here.
Keywords: vascular senescence; quality control; senescence; receptor ... See more keywords
A potential role of autophagy-mediated vascular senescence in the pathophysiology of HFpEF
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.1057349
Abstract: Heart failure with preserved ejection fraction (HFpEF) is one of the most complex and most prevalent cardiometabolic diseases in aging population. Age, obesity, diabetes, and hypertension are the main comorbidities of HFpEF. Microvascular dysfunction and… read more here.
Keywords: vascular senescence; autophagy mediated; role; senescence ... See more keywords
NADPH Oxidases and Mitochondria in Vascular Senescence
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DOI: 10.3390/ijms19051327
Abstract: Aging is the major risk factor in the development of cardiovascular diseases (CVDs), including hypertension, atherosclerosis, and myocardial infarction. Oxidative stress caused by overproduction of reactive oxygen species (ROS) and/or by reduced expression of antioxidant… read more here.
Keywords: oxidases mitochondria; mitochondria vascular; senescence; nadph oxidases ... See more keywords