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Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202203995
Abstract: Vascular smooth muscle cells (SMCs) can adapt to changes in cellular geometric cues; however, the underlying mechanisms remain elusive. Using 2D micropatterned substrates to engineer cell geometry, it is found that in comparison with an…
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Keywords:
dna;
muscle cells;
geometry;
vascular smooth ... See more keywords
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Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202204038
Abstract: Abdominal aortic aneurysm (AAA) is a common vascular disease associated with significant phenotypic alterations in vascular smooth muscle cells (VSMCs). Gasdermin D (GSDMD) is a pore‐forming effector of pyroptosis. In this study, the role of…
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Keywords:
muscle cells;
abdominal aortic;
vascular smooth;
aortic aneurysm ... See more keywords
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Published in 2018 at "ChemBioChem"
DOI: 10.1002/cbic.201700683
Abstract: Diazeniumdiolates (NONOates) are a class of nitric‐oxide‐releasing substances widely used in studies of NO/cGMP signalling. Because spatiotemporal control is highly desirable for such purposes, we have synthesised a new Npom‐caged pyrrolidine NONOate. A kinetic analysis…
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Keywords:
vascular smooth;
cgmp signalling;
muscle cells;
npom protected ... See more keywords
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Published in 2023 at "Cell Biology International"
DOI: 10.1002/cbin.11982
Abstract: Tribbles homolog 2 (TRIB2) functions as an adapter protein that regulates signal transductions involved in a variety of cellular functions, including tumorigenesis. However, the role of TRIB2 in the proliferation of vascular smooth muscle cells…
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Keywords:
cell;
proliferation;
role;
expression ... See more keywords
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Published in 2018 at "Journal of biophotonics"
DOI: 10.1002/jbio.201700005
Abstract: An understanding of deformation of cardiovascular tissue under hemodynamic load is crucial for understanding the health and disease of blood vessels. In the present work, an epi-detected stimulated Raman scattering (epi-SRS) imaging platform was designed…
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Keywords:
raman scattering;
detected stimulated;
stimulated raman;
vascular smooth ... See more keywords
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Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23091
Abstract: Nuclear receptor subfamily 6 group A member 1 (NR6A1) is involved in promoting the apoptotic process of vascular smooth muscle cells (VSMCs) which is a critical process involved in atherosclerosis, but the action mechanism remains…
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Keywords:
lubac;
apoptosis;
muscle cells;
vascular smooth ... See more keywords
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Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29272
Abstract: In this study, we established both an animal model and a cellular model of hyperuricemia (HUC). Subsequently, we treated these models with allopurinol (ALLO) to study the effect of uric acid (UA) and ALLO on…
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Keywords:
osteoblasts vascular;
vascular smooth;
muscle cells;
proliferation osteoblasts ... See more keywords
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Published in 2023 at "Journal of cellular biochemistry"
DOI: 10.1002/jcb.30422
Abstract: Cardiovascular diseases (CVDs) are associated with vascular smooth muscle cell (VSMC) and endothelial cell (EC) damage. Angiotensin1-7 (Ang1-7) and B-type natriuretic peptide (BNP) are responsible for vasodilation and regulation of blood flow. These protective effects of BNP are primarily…
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Keywords:
stress;
smooth muscle;
oxidative stress;
vascular smooth ... See more keywords
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Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.25903
Abstract: Intercellular communication among autonomic nerves, endothelial cells (ECs), and vascular smooth muscle cells (VSMCs) plays a central role in an uninterrupted regulation of blood flow through vascular contractile machinery. Impairment of this communication is linked…
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Keywords:
vascular smooth;
muscle cells;
smooth muscle;
activation ... See more keywords
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Published in 2018 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.ce0618-236r
Abstract: Sepsis is a deadly syndrome characterized by organ dysfunction and failure following an infection. The body’s response to infection is designed to limit the spread of pathogens and to facilitate clearance of the invading microorganisms.…
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Keywords:
sepsis;
response;
vascular smooth;
smooth muscle ... See more keywords
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Published in 2018 at "Inflammation Research"
DOI: 10.1007/s00011-018-1178-z
Abstract: ObjectiveIL-1β secretion by the inflammasome is strictly controlled and requires two sequential signals: a priming signal and an activating signal. Lysosomal membrane permeabilization (LMP) plays a critical role in the regulation of NLRP3 inflammasome, and…
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Keywords:
secretion;
vascular smooth;
human vascular;
lysosomal membrane ... See more keywords