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   Articles with "vascular tone" as a keyword



Unraveling the complexity of vascular tone regulation: a multiscale computational approach to integrating chemo-mechano-biological pathways with cardiovascular biomechanics

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recommendations! Published in 2024 at "Biomechanics and Modeling in Mechanobiology"

DOI: 10.1007/s10237-024-01826-6

Abstract: Vascular tone regulation is a crucial aspect of cardiovascular physiology, with significant implications for overall cardiovascular health. However, the precise physiological mechanisms governing smooth muscle cell contraction and relaxation remain uncertain. The complexity of vascular… read more here.

Keywords: chemo mechano; tone regulation; biomechanics; vascular tone ... See more keywords

Photoplethysmographic characterization of vascular tone mediated changes in arterial pressure: an observational study

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recommendations! Published in 2018 at "Journal of Clinical Monitoring and Computing"

DOI: 10.1007/s10877-018-0235-z

Abstract: AbstractTo determine whether a classification based on the contour of the photoplethysmography signal (PPGc) can detect changes in systolic arterial blood pressure (SAP) and vascular tone. Episodes of normotension (SAP 90–140 mmHg), hypertension (SAP > 140 mmHg) and hypotension… read more here.

Keywords: changes arterial; tone; mmhg; vascular tone ... See more keywords
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COPD: Should Diagnosis Match Physiology?

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recommendations! Published in 2020 at "Chest"

DOI: 10.1016/j.chest.2019.09.039

Abstract: that the underlying mechanism(s) motivating the use of vasopressor(s) must be kept in mind. Increasing BP by a pressor combination increasing the vascular tone via different mechanisms might be correct. This approach will work well… read more here.

Keywords: copd diagnosis; diagnosis match; vascular tone; physiology ... See more keywords

Epigenetic down-regulation of BKCa channel by miR-181a contributes to the fetal and neonatal nicotine-mediated exaggerated coronary vascular tone in adult life.

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recommendations! Published in 2019 at "International journal of cardiology"

DOI: 10.1016/j.ijcard.2019.01.099

Abstract: BACKGROUND Fetal origin of adult cardiovascular disease is one of the most pressing public concerns and economic problem in modern life. Maternal cigarette smoking/nicotine abuse increases the risk of cardiovascular disease in offspring. However, the… read more here.

Keywords: nicotine; coronary vascular; vascular tone; bkca ... See more keywords

Thrombin induces a temporal biphasic vascular response through the differential phosphorylation of endothelial nitric oxide synthase via protease-activated receptor-1 and protein kinase C.

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recommendations! Published in 2022 at "Journal of pharmacological sciences"

DOI: 10.1016/j.jphs.2022.02.001

Abstract: Endothelial nitric oxide synthase (eNOS) is a critical regulatory enzyme that controls vascular tone via the production of nitric oxide. Although thrombin also modulates vascular tone predominantly via the activation of protease-activated receptors (PARs), the… read more here.

Keywords: response; vascular tone; nitric oxide; differential phosphorylation ... See more keywords

Deoxycholylglycine, a conjugated secondary bile acid, reduces vascular tone by attenuating Ca2+ sensitivity via rho kinase pathway

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recommendations! Published in 2018 at "Toxicology and Applied Pharmacology"

DOI: 10.1016/j.taap.2018.04.012

Abstract: ABSTRACT Patients with cirrhosis have reduced systemic vascular resistance and elevated circulating bile acids (BAs). Previously, we showed that secondary conjugated BAs impair vascular tone by reducing vascular smooth muscle cell (VSMC) Ca2+ influx. In… read more here.

Keywords: ca2 sensitivity; tone; vascular tone; vasoconstriction ... See more keywords
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Sphingosine 1-phosphate-induced nitric oxide production simultaneously controls endothelial barrier function and vascular tone in resistance arteries.

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recommendations! Published in 2021 at "Vascular pharmacology"

DOI: 10.1016/j.vph.2021.106874

Abstract: The regulations of endothelial permeability and vascular tone by the sphingosine 1-phosphate (S1P) have been well-studied independently. Little is known about whether effects of S1P on endothelial permeability can directly influence vascular tone in resistance… read more here.

Keywords: barrier; resistance arteries; tone; vascular tone ... See more keywords

Endothelial TrkB receptor activation controls vascular tone of rat middle cerebral artery.

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recommendations! Published in 2021 at "Vascular pharmacology"

DOI: 10.1016/j.vph.2021.106930

Abstract: Little is known on the cerebrovascular BDNF (brain-derived neurotrophic factor)/TrkB (tropomyosin related kinase B) pathway. This study investigated the contribution of endogenous endothelial BDNF to the control of vascular tone of rat middle cerebral artery… read more here.

Keywords: tone; vascular tone; endothelial bdnf; tone rat ... See more keywords

Vascular mechanoreceptor magnetic activation, hemodynamic evidence and potential clinical outcomes

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recommendations! Published in 2025 at "Electromagnetic Biology and Medicine"

DOI: 10.1080/15368378.2025.2468248

Abstract: ABSTRACT There is sufficient proof that static magnetic fields (SMFs) of different parameters have a significant effect on the cardiovascular system. The sometimes contradictory, opposite-directional nature of SMF’s hemodynamic effect generates uncertainty; therefore, an explanation… read more here.

Keywords: physiology; mechanoreceptor magnetic; magnetic activation; vascular tone ... See more keywords

SUSTAINED POTENTIATION OF  1-ADRENERGIC VASOCONSTRICTION BY SPHINGOSINE 1-PHOSPHATE

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recommendations! Published in 2018 at "Journal of Hypertension"

DOI: 10.1097/01.hjh.0000539850.36125.62

Abstract: Objective: In our present project we aimed to examine the vasoactive effects of sphingosine 1-phosphate (S1P) by evaluating its capability to alter the basal vascular tone and to influence vasoconstriction mediated by &agr;1-adrenoreceptors Design and… read more here.

Keywords: vascular tone; effect; sphingosine phosphate; vasoconstriction ... See more keywords

Role of renal vascular potassium channels in physiology and pathophysiology

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recommendations! Published in 2017 at "Acta Physiologica"

DOI: 10.1111/apha.12882

Abstract: The control of renal vascular tone is important for the regulation of salt and water balance, blood pressure and the protection against damaging elevated glomerular pressure. The K+ conductance is a major factor in the… read more here.

Keywords: role renal; renal vascular; vascular tone; physiology ... See more keywords