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Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202401856
Abstract: Tissue vascularization plays a critical role in the regeneration and repair of damaged tissues. However, in certain instances of tissue injury, the pace and effectiveness of vascularization can be limited. Innovative strategies leveraging magnetic fields…
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Keywords:
vascularization;
tissue vascularization;
magnetically controlled;
controlled strategies ... See more keywords
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Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200922
Abstract: Implanted cell‐containing grafts require a robust and functional vasculature to supply oxygen and nutrients, as well as clear metabolic waste products. However, it remains challenging to fabricate tunable, vascular‐promoting scaffolds without incorporating additional biologics. Here,…
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Keywords:
engineering hierarchical;
vascularization;
hierarchical biphasic;
gel ... See more keywords
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Published in 2022 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202201784
Abstract: Previous studies have developed vascularized tumor spheroid models to demonstrate the impact of intravascular flow on tumor progression and treatment. However, these models have not been widely adopted so the vascularization of tumor spheroids in…
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Keywords:
new strategy;
vascularization;
tumor spheroids;
tumor ... See more keywords
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Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300607
Abstract: The formation of multiscale vascular networks is essential for the in vitro construction of large-scale biomimetic cardiac tissues/organs. Although a variety of bioprinting processes have been developed to achieve the construction of mesoscale and large-scale…
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Keywords:
electrical stimulation;
vascularization;
stimulation promotes;
stimulation ... See more keywords
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Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202400977
Abstract: Vasculature is crucial for maintaining organ homeostasis and metabolism. Although 3D organoids can mimic organ structures and patterns, they still lack vascular systems, limiting the recapitulation of physiological complexities. Although vascularization of organoids has been…
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Keywords:
vascularization;
intestinal organoid;
network formation;
vascular network ... See more keywords
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Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202402045
Abstract: Tissue vascularization is a major bottleneck in tissue engineering. In this review, the state of the art on the intricate role of hyaluronic acid (HA) in angiogenesis is explored. HA plays a twofold role in…
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Keywords:
vascularization;
role;
tissue engineering;
hyaluronic acid ... See more keywords
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Published in 2025 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202500301
Abstract: Organoids provide 3D structures that replicate native tissues in biomedical research. The development of vascular networks within organoids enables oxygen and nutrient delivery while facilitating metabolic waste removal, which supports organoid growth and maturation. Recent…
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Keywords:
organoid vascularization;
vascularization;
strategies applications;
vascularization strategies ... See more keywords
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Published in 2025 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202501390
Abstract: Bone tissue is highly vascularized, and robust blood flow is critical for successful bone regeneration. However, the intricate architecture of bone vascular networks and the mechanisms governing their development remain poorly understood, necessitating the development…
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Keywords:
differentiation;
cell localization;
vascularization;
cell ... See more keywords
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Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28189
Abstract: Vascularization is a critical but challenging process in developing functional bioengineered livers with the decellularized liver scaffolds (DLSs) and the process is accompanied by cell‐specific metabolic alterations. To elucidate the dynamic alterations of metabolites during…
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Keywords:
vascularization progression;
alterations metabolites;
vascularization;
revealed vascularization ... See more keywords
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Published in 2019 at "Comprehensive Physiology"
DOI: 10.1002/cphy.c180037
Abstract: The ability to generate new microvessels in desired numbers and at desired locations has been a long-sought goal in vascular medicine, engineering, and biology. Historically, the need to revascularize ischemic tissues nonsurgically (so-called therapeutic vascularization)…
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Keywords:
medicine;
engineering;
microvasculature;
vascularization ... See more keywords
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Published in 2020 at "Stem Cells Translational Medicine"
DOI: 10.1002/sctm.19-0207
Abstract: While human adipose‐derived stem cells (hADSCs) are known to possess osteogenic differentiation potential, the bone tissues formed are generally considered rudimentary and immature compared with those made by bone‐derived precursor cells such as human bone…
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Keywords:
vascularization;
osteogenic maturation;
bone;
bone derived ... See more keywords