Engineering Photocrosslinkable Bicomponent Hydrogel Constructs for Creating 3D Vascularized Bone
Sign Up to like & getrecommendations! Published in 2017 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201601122
Abstract: Engineering bone tissue requires the generation of a highly organized vasculature. Cellular behavior is affected by the respective niche. Directing cellular behavior and differentiation for creating mineralized regions surrounded by vasculature can be achieved by… read more here.
Keywords: engineering; hydrogel; engineering photocrosslinkable; vascularized bone ... See more keywords
Bioelectrically Reprogramming Hydrogels Rejuvenate Vascularized Bone Regeneration in Senescence
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202403837
Abstract: Senescent bone tissue displays a pathological imbalance characterized by decreased angiogenesis, disrupted bioelectric signaling, ion dysregulation, and reduced stem cell differentiation. Once bone defects occur, this pathological imbalance makes them difficult to repair. An innovative… read more here.
Keywords: hydrogel; vascularized bone; bone regeneration; bone ... See more keywords
Mussel‐Derived and Bioclickable Peptide Mimic for Enhanced Interfacial Osseointegration via Synergistic Immunomodulation and Vascularized Bone Regeneration
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202401833
Abstract: Inadequate osseointegration at the interface is a key factor in orthopedic implant failure. Mechanistically, traditional orthopedic implant interfaces fail to precisely match natural bone regeneration processes in vivo. In this study, a novel biomimetic coating… read more here.
Keywords: bone regeneration; osseointegration; immunomodulation vascularized; vascularized bone ... See more keywords
Comparative meta‐analysis on the various vascularized bone flaps used for the treatment of scaphoid nonunion
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Orthopaedic Research"
DOI: 10.1002/jor.23242
Abstract: We did a meta‐analysis of the literature in order to clarify which of the vascularized bone flaps (VBF) used for scaphoid non‐union treatment has the best outcome with regard to various parameters. We analyzed 54… read more here.
Keywords: analysis; vascularized bone; bone flaps; flaps used ... See more keywords
Vascular Derived ECM Improves Therapeutic Index of BMP-2 and Drives Vascularized Bone Regeneration.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202107991
Abstract: Vascularized osteogenesis is essential for successful bone regeneration, yet its realization during large size bone defect healing remains challenging due to the difficulty to couple multiple biological processes. Herein, harnessing the intrinsic angiogenic potential of… read more here.
Keywords: vascular derived; bone; bone regeneration; therapeutic index ... See more keywords
[Scaphoid pseudarthrosis : Complex reconstruction using vascularized bone grafts].
Sign Up to like & getrecommendations! Published in 2019 at "Der Unfallchirurg"
DOI: 10.1007/s00113-019-0609-9
Abstract: The most important goals of scaphoid reconstruction in pseudarthrosis are correction of the humpback deformity, the realignment of the proximal carpal row and the bony union of the scaphoid. Therefore, in most cases bone grafting… read more here.
Keywords: bone grafts; reconstruction; fusion rates; vascularized bone ... See more keywords
Human adipose-derived stem cell spheroids incorporating platelet-derived growth factor (PDGF) and bio-minerals for vascularized bone tissue engineering.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2020.120192
Abstract: Stem cells with mineralized materials have been used for bone regeneration; however, engineering the complex vascularized structure of the natural bone remains a challenge. Here, we developed platelet-derived growth factor (PDGF) and bio-mineral coated fibers… read more here.
Keywords: pdgf bio; vascularized bone; bone; stem ... See more keywords
Engineering pre-vascularized bone-like tissue from human mesenchymal stem cells through simulating endochondral ossification.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2022.121451
Abstract: Currently, most in vitro engineered bone tissues do not contain viable blood vessel systems, so the vascularization depends on post-implantation angiogenesis from the host, which is often insufficient for repairing large bone defects. In this… read more here.
Keywords: like constructs; bone; bone like; hbmscs ... See more keywords
Does Anyone Need a Vascularized Graft?
Sign Up to like & getrecommendations! Published in 2019 at "Hand clinics"
DOI: 10.1016/j.hcl.2019.03.005
Abstract: Many hand surgeons argue that vascularized bone grafting is indicated in proximal pole avascular necrosis, prior failed surgery, or long-standing scaphoid nonunion. However, the available evidence does not support improved treatment outcomes for vascularized bone… read more here.
Keywords: need vascularized; bone grafting; vascularized bone; anyone need ... See more keywords
Plant-Derived Polyphenol and LL-37 Peptide-Modified Nanofibrous Scaffolds for Promotion of Antibacterial Activity, Anti-Inflammation, and Type-H Vascularized Bone Regeneration.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c20776
Abstract: The regeneration of oral tissues is a challenging clinical problem because of the complex microbial and biological stress environments. Electrospun fibrous scaffolds have attracted significant interest as effective barrier membranes for guided bone regeneration (GBR);… read more here.
Keywords: regeneration; fibrous scaffold; type vascularized; bone regeneration ... See more keywords
Surgeon‐Based 3D Printing for Microvascular Bone Flaps
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Reconstructive Microsurgery"
DOI: 10.1055/s-0037-1600133
Abstract: Background Three‐dimensional (3D) printing has developed as a revolutionary technology with the capacity to design accurate physical models in preoperative planning. We present our experience in surgeon‐based design of 3D models, using home 3D software… read more here.
Keywords: based printing; vascularized bone; surgeon based; printing ... See more keywords