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Published in 2017 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201601122
Abstract: Engineering bone tissue requires the generation of a highly organized vasculature. Cellular behavior is affected by the respective niche. Directing cellular behavior and differentiation for creating mineralized regions surrounded by vasculature can be achieved by…
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Keywords:
engineering;
hydrogel;
engineering photocrosslinkable;
vascularized bone ... See more keywords
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Published in 2017 at "Journal of Orthopaedic Research"
DOI: 10.1002/jor.23242
Abstract: We did a meta‐analysis of the literature in order to clarify which of the vascularized bone flaps (VBF) used for scaphoid non‐union treatment has the best outcome with regard to various parameters. We analyzed 54…
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Keywords:
analysis;
vascularized bone;
bone flaps;
flaps used ... See more keywords
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Published in 2022 at "Small"
DOI: 10.1002/smll.202107991
Abstract: Vascularized osteogenesis is essential for successful bone regeneration, yet its realization during large size bone defect healing remains challenging due to the difficulty to couple multiple biological processes. Herein, harnessing the intrinsic angiogenic potential of…
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Keywords:
vascular derived;
bone;
bone regeneration;
therapeutic index ... See more keywords
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Published in 2019 at "Der Unfallchirurg"
DOI: 10.1007/s00113-019-0609-9
Abstract: The most important goals of scaphoid reconstruction in pseudarthrosis are correction of the humpback deformity, the realignment of the proximal carpal row and the bony union of the scaphoid. Therefore, in most cases bone grafting…
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Keywords:
bone grafts;
reconstruction;
fusion rates;
vascularized bone ... See more keywords
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Published in 2020 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2020.120192
Abstract: Stem cells with mineralized materials have been used for bone regeneration; however, engineering the complex vascularized structure of the natural bone remains a challenge. Here, we developed platelet-derived growth factor (PDGF) and bio-mineral coated fibers…
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Keywords:
pdgf bio;
vascularized bone;
bone;
stem ... See more keywords
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Published in 2022 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2022.121451
Abstract: Currently, most in vitro engineered bone tissues do not contain viable blood vessel systems, so the vascularization depends on post-implantation angiogenesis from the host, which is often insufficient for repairing large bone defects. In this…
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Keywords:
like constructs;
bone;
bone like;
hbmscs ... See more keywords
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Published in 2019 at "Hand clinics"
DOI: 10.1016/j.hcl.2019.03.005
Abstract: Many hand surgeons argue that vascularized bone grafting is indicated in proximal pole avascular necrosis, prior failed surgery, or long-standing scaphoid nonunion. However, the available evidence does not support improved treatment outcomes for vascularized bone…
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Keywords:
need vascularized;
bone grafting;
vascularized bone;
anyone need ... See more keywords
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Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c20776
Abstract: The regeneration of oral tissues is a challenging clinical problem because of the complex microbial and biological stress environments. Electrospun fibrous scaffolds have attracted significant interest as effective barrier membranes for guided bone regeneration (GBR);…
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Keywords:
regeneration;
fibrous scaffold;
type vascularized;
bone regeneration ... See more keywords
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Published in 2017 at "Journal of Reconstructive Microsurgery"
DOI: 10.1055/s-0037-1600133
Abstract: Background Three‐dimensional (3D) printing has developed as a revolutionary technology with the capacity to design accurate physical models in preoperative planning. We present our experience in surgeon‐based design of 3D models, using home 3D software…
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Keywords:
based printing;
vascularized bone;
surgeon based;
printing ... See more keywords
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Published in 2022 at "Biofabrication"
DOI: 10.1088/1758-5090/ac6700
Abstract: The integration of three-dimensional (3D) bioprinted scaffold’s structure and function for critical-size bone defect repair is of immense significance. Inspired by the basic component of innate cortical bone tissue—osteons, many studies focus on biomimetic strategy.…
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Keywords:
vascularized bone;
mimetic scaffolds;
bone tissue;
osteon mimetic ... See more keywords
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Published in 2023 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.1003861
Abstract: Introduction: Durable reconstruction of critical size bone defects is still a surgical challenge despite the availability of numerous autologous and substitute bone options. In this paper, we have investigated the possibility of creating a living…
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Keywords:
bone;
vascularized bone;
model;
differentiation ... See more keywords