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Published in 2019 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201801433
Abstract: Bone tissue is a highly vascularized tissue and concomitant development of the vascular system and mineralized matrix requires a synergistic interaction between osteogenesis and angioblasts. Several strategies have been applied to achieve vascularized tissue-engineered bone,…
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Keywords:
vascularized tissue;
regeneration;
engineered bone;
tissue ... See more keywords
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Published in 2019 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2019.04.024
Abstract: In this study, the potential of vascularized tissue-engineered bone constructed by a double cell-sheet (DCS) complex and polylysine (PLL)-modified coralline hydroxyapatite (CHA) to repair large radius bone defects was investigated in rabbits. Firstly, the DCS…
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Keywords:
pll cha;
vascularized tissue;
cha;
bone ... See more keywords
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Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-14923-7
Abstract: The repair of large bone defects with complex geometries remains a major clinical challenge. Here, we explored the feasibility of fabricating polylactic acid-hydroxyapatite (PLA-HA) composite scaffolds. These scaffolds were constructed from vascularized tissue engineered bone…
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Keywords:
vascularized tissue;
engineered bone;
bone;
tissue engineered ... See more keywords
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Published in 2021 at "Medicine"
DOI: 10.1097/md.0000000000025907
Abstract: Abstract If wounds are infected with bacteria resistant to an empirical antibiotic regimen, effective wound treatment will be delayed. This can delay wound healing and lengthen hospital stays, increasing the costs to patients. Long-term antibiotic…
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Keywords:
vascularized tissue;
healing time;
infected wound;
tissue ... See more keywords
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Published in 2019 at "Annals of Plastic Surgery"
DOI: 10.1097/sap.0000000000001652
Abstract: Introduction Radiation therapy (RT) is recommended for appropriately selected sarcoma patients to minimize the risk of local recurrence and to maximize outcomes of disease-free survival and function. The purpose of this study was to confirm…
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Keywords:
reconstruction;
sarcoma;
vascularized tissue;
irradiated sarcoma ... See more keywords
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Published in 2021 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2021.685507
Abstract: A wide variety of experimental models including 2D cell cultures, model organisms, and 3D in vitro models have been developed to understand pathophysiological phenomena and assess the safety and efficacy of potential therapeutics. In this…
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Keywords:
vascularized tissue;
bioprinting based;
based vascularized;
tissue models ... See more keywords
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Published in 2023 at "Bioengineering"
DOI: 10.3390/bioengineering10020124
Abstract: Tissue organoids hold enormous potential as tools for a variety of applications, including disease modeling and drug screening. To effectively mimic the native tissue environment, it is critical to integrate a microvasculature with the parenchyma…
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Keywords:
tissue organoids;
vascularized tissue;
tissue;
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Published in 2023 at "Polymers"
DOI: 10.3390/polym15092015
Abstract: Blood vessels not only transport oxygen and nutrients to each organ, but also play an important role in the regulation of tissue regeneration. Impaired or occluded vessels can result in ischemia, tissue necrosis, or even…
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Keywords:
vascularized tissue;
tissue engineering;
current strategies;
vascular grafts ... See more keywords