New Strategy for Promoting Vascularization in Tumor Spheroids in a Microfluidic Assay
Sign Up to like & getrecommendations! Published in 2022 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202201784
Abstract: Previous studies have developed vascularized tumor spheroid models to demonstrate the impact of intravascular flow on tumor progression and treatment. However, these models have not been widely adopted so the vascularization of tumor spheroids in… read more here.
Keywords: new strategy; vascularization; tumor spheroids; tumor ... See more keywords
All‐in‐one microfluidic design to integrate vascularized tumor spheroid into high‐throughput platform
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28221
Abstract: The development of a scalable and highly reproducible in vitro tumor microenvironment (TME) platform still sheds light on new insights into cancer metastasis mechanisms and anticancer therapeutic strategies. Here, we present an all‐in‐one injection molded… read more here.
Keywords: high throughput; spheroid; vascularized tumor; tumor ... See more keywords
Vascularized tumor models for the evaluation of drug delivery systems: a paradigm shift
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DOI: 10.1007/s13346-024-01580-3
Abstract: As the conversion rate of preclinical studies for cancer treatment is low, user-friendly models that mimic the pathological microenvironment and drug intake with high throughput are scarce. Animal models are key, but an alternative to… read more here.
Keywords: drug delivery; delivery systems; vascularized tumor; drug ... See more keywords
Abstract LB447: Drug delivery and efficacy testing using vascularized tumor-on-a-chip
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DOI: 10.1158/1538-7445.am2024-lb447
Abstract: The inhibition of tumor angiogenesis is considered a promising strategy to impede cancer progression, as the vasculature associated with tumors plays a crucial role in supplying blood and facilitating metastasis. Therefore, the in vitro replication… read more here.
Keywords: cancer; vascularized tumor; hybrid spheroids; tumor ... See more keywords
Recent advances in vascularized tumor-on-a-chip
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1150332
Abstract: The vasculature plays a critical role in cancer progression and metastasis, representing a pivotal aspect in the creation of cancer models. In recent years, the emergence of organ-on-a-chip technology has proven to be a robust… read more here.
Keywords: chip; vascularized tumor; tumor chip; advances vascularized ... See more keywords