Targeting vasculogenic mimicry by phytochemicals: A potential opportunity for cancer therapy
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DOI: 10.1002/iub.2233
Abstract: Vasculogenic mimicry (VM) is regarded as a process where very aggressive cancer cells generate vascular‐like patterns without the presence of endothelial cells. It is considered as the main mark of malignant cancer and has pivotal… read more here.
Keywords: therapy; vasculogenic mimicry; targeting vasculogenic; mimicry phytochemicals ... See more keywords
Expression profiling of long noncoding RNAs associated with vasculogenic mimicry in osteosarcoma
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DOI: 10.1002/jcb.28514
Abstract: Osteosarcoma (OS) is the most common highly malignant bone tumor in teens. Vasculogenic mimicry (VM) is defined as de novo extracellular matrix‐rich vascular‐like networks formed by highly aggressive tumor cells. We previously reported the presence… read more here.
Keywords: long noncoding; vasculogenic mimicry; formation; expression ... See more keywords
Myricetin reverses epithelial–endothelial transition and inhibits vasculogenic mimicry and angiogenesis of hepatocellular carcinoma by directly targeting PAR1
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7427
Abstract: Most antiangiogenic inhibitors targeting endothelium‐dependent vessels cannot inhibit tumor growth but promote tumor invasion and metastasis in some patients. Vasculogenic mimicry (VM) employs mechanisms that differ from those used to construct endothelium‐dependent vessels. Inhibiting VM… read more here.
Keywords: hepatocellular carcinoma; myricetin; vasculogenic mimicry; invasion ... See more keywords
LncRNA PVT1 induces aggressive vasculogenic mimicry formation through activating the STAT3/Slug axis and epithelial-to-mesenchymal transition in gastric cancer
Sign Up to like & getrecommendations! Published in 2020 at "Cellular Oncology"
DOI: 10.1007/s13402-020-00532-6
Abstract: Vasculogenic mimicry (VM), a vessel-like network formed by highly aggressive tumor cells, plays an important role in accelerating cancer progression. This special vascularization pattern is closely associated with a poor prognosis in various cancers. As… read more here.
Keywords: gastric cancer; pvt1; vasculogenic mimicry; formation ... See more keywords
Cell-dependent regulation of vasculogenic mimicry by carcinoembryonic antigen cell adhesion molecule 1 (CEACAM1)
Sign Up to like & getrecommendations! Published in 2020 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2020.100734
Abstract: Vasculogenic mimicry (VM) promotes tumor migration, metastasis, and invasion in various types of cancer, but the relationship between VM and these phenotypes remains undefined. In this study, we examined carcinoembryonic antigen cell adhesion molecule 1… read more here.
Keywords: ceacam1; vasculogenic mimicry; cell adhesion; carcinoembryonic antigen ... See more keywords
Vasculogenic mimicry structures in melanoma support the recruitment of monocytes
Sign Up to like & getrecommendations! Published in 2022 at "Oncoimmunology"
DOI: 10.1080/2162402x.2022.2043673
Abstract: ABSTRACT The progression of cancer is facilitated by infiltrating leukocytes which can either actively kill cancer cells or promote their survival. Our current understanding of leukocyte recruitment into tumors is largely limited to the adhesion… read more here.
Keywords: adhesion; melanoma; recruitment; adhesion molecules ... See more keywords
Evodiamine inhibits vasculogenic mimicry in HCT116 cells by suppressing hypoxia-inducible factor 1-alpha-mediated angiogenesis.
Sign Up to like & getrecommendations! Published in 2020 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000001030
Abstract: Evodiamine (Evo), a quinazoline alkaloid and one of the most typical polycyclic heterocycles, is mainly isolated from Evodia rugulosa. Vasculogenic mimicry (VM) is a newly identified way of angiogenesis during tumor neovascularization, which is prevalent… read more here.
Keywords: hypoxia inducible; hct116; vasculogenic mimicry; factor alpha ... See more keywords
Long noncoding RNA n339260 promotes vasculogenic mimicry and cancer stem cell development in hepatocellular carcinoma
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DOI: 10.1111/cas.13740
Abstract: Vasculogenic mimicry (VM) refers to the unique capability of aggressive tumor cells to mimic the pattern of embryonic vasculogenic networks. Cancer stem cells (CSC) represent a subpopulation of tumor cells endowed with the capacity for… read more here.
Keywords: csc; n339260; cancer stem; vasculogenic mimicry ... See more keywords
N6‐methyladenosine‐modified HOTAIRM1 promotes vasculogenic mimicry formation in glioma
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DOI: 10.1111/cas.15578
Abstract: Vasculogenic mimicry (VM) has been reported to accelerate angiogenesis in malignant tumors, yet the mechanism underlying VM has not been fully elucidated. N6‐methyladenosine (m6A) mainly modulates mRNA fate and affects multiple tumorigenesis. Here, we aimed… read more here.
Keywords: formation glioma; modified hotairm1; formation; hotairm1 ... See more keywords
MMP‐2 and MMP‐13 affect vasculogenic mimicry formation in large cell lung cancer
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DOI: 10.1111/jcmm.13283
Abstract: Matrix metalloproteinases (MMPs) have critical functions in tumour vasculogenic mimicry (VM). This study explored the mechanisms underlying MMP‐13 and MMP‐2 regulation of tumour VM formation in large cell lung cancer (LCLC). In our study, laminin5… read more here.
Keywords: formation large; vasculogenic mimicry; mmp; formation ... See more keywords
LOXL2 promotes vasculogenic mimicry and tumour aggressiveness in hepatocellular carcinoma
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DOI: 10.1111/jcmm.14039
Abstract: Lysyl oxidase‐like 2 (LOXL2) has shown to promote metastasis and poor prognosis in hepatocellular carcinoma (HCC). Also, we have previously reported that vasculogenic mimicry (VM) is associated with invasion, metastasis and poor survival in HCC… read more here.
Keywords: hepatocellular carcinoma; hcc; loxl2; vasculogenic mimicry ... See more keywords