Lactated Ringer vs Normal Saline Solution During Sickle Cell Vaso-Occlusive Episodes.
Sign Up to like & getrecommendations! Published in 2024 at "JAMA internal medicine"
DOI: 10.1001/jamainternmed.2024.4428
Abstract: Importance Sickle cell disease (SCD), a clinically heterogenous genetic hemoglobinopathy, is characterized by painful vaso-occlusive episodes (VOEs) that can require hospitalization. Patients admitted with VOEs are often initially resuscitated with normal saline (NS) to improve… read more here.
Keywords: lactated ringer; normal saline; occlusive episodes; sickle cell ... See more keywords
The role of carbon monoxide and heme oxygenase in the prevention of sickle cell disease vaso‐occlusive crises
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Hematology"
DOI: 10.1002/ajh.24750
Abstract: Sickle Cell Disease (SCD) is a painful, lifelong hemoglobinopathy inherited as a missense point mutation in the hemoglobin (Hb) beta‐globin gene. This disease has significant impact on quality of life and mortality, thus a substantial… read more here.
Keywords: occlusive crises; heme; vaso occlusive; disease ... See more keywords
Inflammatory and endothelial markers during vaso‐occlusive crisis and acute chest syndrome in sickle cell disease
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Hematology"
DOI: 10.1002/ajh.24868
Abstract: AA. Prognostic relevance of morphological classification models for myelodysplastic syndromes in an era of the revised International Prognostic Scoring System. Eur J Cancer. 2016;56:10–20. [17] van Spronsen MF, Witte BI, Ossenkoppele GJ, Westers TM, van… read more here.
Keywords: inflammatory endothelial; endothelial markers; vaso occlusive; markers vaso ... See more keywords
Visual recovery and vascular reperfusion after vaso-occlusive retinopathy from anti-phospholipid syndrome associated with systemic lupus erythematosus
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Ophthalmology Case Reports"
DOI: 10.1016/j.ajoc.2020.100763
Abstract: Purpose To report a case of visual recovery and vascular reperfusion after vaso-occlusive retinopathy from anti-phospholipid syndrome associated with systemic lupus erythematosus. Observations A 15-year-old boy with a known diagnosis of systemic lupus erythematosus and… read more here.
Keywords: systemic lupus; vaso occlusive; lupus erythematosus; reperfusion ... See more keywords
Blockade of placental growth factor reduces vaso-occlusive complications in murine models of sickle cell disease.
Sign Up to like & getrecommendations! Published in 2018 at "Experimental hematology"
DOI: 10.1016/j.exphem.2018.01.002
Abstract: Vaso-occlusive crisis (VOC) is the most common and debilitating complication of sickle cell disease (SCD); recurrent episodes cause organ damage and contribute to early mortality. Plasma placental growth factor (PlGF) levels are elevated in SCD… read more here.
Keywords: plgf; placental growth; vaso occlusive; cell disease ... See more keywords
Impact of antithrombotic agents on outcomes in patients requiring surgery for chronic subdural haematoma: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2024 at "British Journal of Neurosurgery"
DOI: 10.1080/02688697.2024.2333399
Abstract: Abstract A chronic subdural haematoma (CSDH) is a collection of aged blood between the dura and the brain, typically treated with surgical evacuation. Many patients with CSDH have comorbidities requiring the use of antithrombotic medications.… read more here.
Keywords: systematic review; chronic subdural; csdh; vaso occlusive ... See more keywords
Acute vaso-occlusive crisis in patients with sickle cell disease.
Sign Up to like & getrecommendations! Published in 2017 at "Nursing"
DOI: 10.1097/01.nurse.0000510745.32219.dd
Abstract: www.Nursing2017.com January l Nursing2017 l 67 SICKLE CELL DISEASE (SCD) is a group of chronic genetic disorders that affects an estimated 70,000 to 80,000 Americans.1 SCD is characterized by abnormal hemoglobin, called hemoglobin S or… read more here.
Keywords: vaso occlusive; acute vaso; cell disease; occlusive crisis ... See more keywords
A Qualitative Systematic Review of Pediatric Patient and Caregiver Perspectives on Pain Management for Vaso-Occlusive Episodes in the Emergency Department
Sign Up to like & getrecommendations! Published in 2023 at "Pediatric Emergency Care"
DOI: 10.1097/pec.0000000000002913
Abstract: Objectives The primary objective of this study is to describe the experiences of pediatric patients with sickle cell disease (SCD) and their caregivers who have presented to the emergency department (ED) for management of vaso-occlusive… read more here.
Keywords: emergency; care; vaso occlusive; management vaso ... See more keywords
Vasoactive and Antifibrotic Properties of Cannabinoids and Applications to Vasospastic/Vaso-Occlusive Disorders
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DOI: 10.1097/sap.0000000000003985
Abstract: Background Management of vasospastic and vaso-occlusive disorders is a complex challenge, with current treatments showing varied success. Cannabinoids have demonstrated both vasodilatory and antifibrotic properties, which present potential mechanisms for therapeutic relief. No existing review… read more here.
Keywords: antifibrotic properties; properties cannabinoids; occlusive disorders; vasospastic vaso ... See more keywords
Real‐World Evidence of Crizanlizumab Showing Reductions in Vaso‐Occlusive Crises and Opioid Usage in Sickle Cell Disease
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DOI: 10.1111/ejh.14323
Abstract: Access to crizanlizumab, a disease‐modifying therapy for sickle cell disease (SCD), was provided through a managed access program (MAP, NCT03720626). The present analysis evaluated the impact of 12 months of crizanlizumab treatment on vaso‐occlusive crises (VOCs),… read more here.
Keywords: disease; cell disease; occlusive crises; vaso occlusive ... See more keywords
High flow oxygen for vaso-occlusive crisis: a multicentre, prospective, randomised, multi-arm, multi-stage clinical trial (OSONE)
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DOI: 10.1136/bmjopen-2025-104564
Abstract: Introduction Sickle cell disease (SCD) is due to the mutation of haemoglobin (Hb), from HbA to HbS and characterised by recurrent vaso-occlusive crises (VOC), which can progress to acute chest syndrome (ACS), a leading cause… read more here.
Keywords: oxygen; multi; trial; stage ... See more keywords