Development of a radioligand for imaging V1a vasopressin receptors with PET.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.08.037
Abstract: A series of vasopressin receptor V1a ligands have been synthesized for positron emission tomography (PET) imaging. The lead compound (1S,5R)-1 ((4-(1H-indol-3-yl)-3-methoxyphenyl) ((1S,5R)-1,3,3-trimethyl-6-azabicyclo[3.2.1]octan-6-yl)methanone) and its F-ethyl analog 6c exhibited the best combination of high binding affinity… read more here.
Keywords: vasopressin receptors; v1a vasopressin; radioligand imaging; development radioligand ... See more keywords
Expression and Function of Vasopressin Receptors in the HT-29 Cell Line.
Sign Up to like & getrecommendations! Published in 2025 at "Current molecular medicine"
DOI: 10.2174/0115665240394070250703050642
Abstract: INTRODUCTION Vasopressin receptors can have different effects on tumorigenesis. The in vitro usage of agonists and antagonists of these receptors can also have a potential impact on developing adjuvant treatment options. Therefore, we aimed to… read more here.
Keywords: colorectal cancer; cancer; vasopressin; function ... See more keywords