Vasorelaxant effect of sinensetin via the NO/sGC/cGMP pathway and potassium and calcium channels
Sign Up to like & getrecommendations! Published in 2018 at "Hypertension Research"
DOI: 10.1038/s41440-018-0083-8
Abstract: Orthosiphon stamineus Benth. (Lambiaceae) is an important traditional plant for the treatment of hypertension. Previous studies have demonstrated that the sinensetin content in O. stamineus is correlated with its vasorelaxant activity. However, there is still… read more here.
Keywords: vasorelaxant effect; blocker; sinensetin; calcium ... See more keywords
Quinazoline-based human phosphodiesterase 5 inhibitors exhibited a selective vasorelaxant effect on rat isolated pulmonary arteries involving NO-sGC-cGMP pathway and calcium inhibitory effects.
Sign Up to like & getrecommendations! Published in 2022 at "Vascular pharmacology"
DOI: 10.2139/ssrn.4197599
Abstract: Phosphodiesterase 5 (PDE5) inhibitors are an attractive option among the currently available therapies in the management of pulmonary arterial hypertension (PAH). Good selectivity for PDE5 is associated with reduced side effects and greater vasorelaxant effect… read more here.
Keywords: vasorelaxant effect; rat isolated; effect; quinazoline based ... See more keywords
Potassium Channels Contributes to Apelin-induced Vasodilation in Rat Thoracic Aorta.
Sign Up to like & getrecommendations! Published in 2022 at "Protein and peptide letters"
DOI: 10.2174/0929866529666220516141317
Abstract: BACKGROUND Apelin is a newly discovered peptide hormone and originally discovered endogenous apelin receptor ligand. OBJECTIVE In this study, we aimed to investigate the possible roles of potassium channel subtypes in the vasorelaxant effect mechanisms… read more here.
Keywords: vasorelaxant effect; pyr1 apelin; effect; rat thoracic ... See more keywords
Vasorelaxant Effect of Prunus mume (Siebold) Siebold & Zucc. Branch through the Endothelium-Dependent Pathway
Sign Up to like & getrecommendations! Published in 2019 at "Molecules"
DOI: 10.3390/molecules24183340
Abstract: Korean plum (Prunus mume (Siebold) Siebold & Zucc.) has long been used as a health food or herbal medicine in Asia. Previous studies have shown that several plants of the genus Prunus have vasodilatory and… read more here.
Keywords: vasorelaxant effect; pathway; prunus mume; endothelium ... See more keywords
Vasorelaxant Mechanism of Herbal Extracts from Mentha suaveolens, Conyza canadensis, Teucrium polium and Salvia verbenaca in the Aorta of Wistar Rats
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27248752
Abstract: Mentha suaveolens (MS), Conyza canadensis (CC), Teucrium polium (TP) and Salvia verbenaca (SV) are used in Morocco to treat hypertension. Our aim was to characterize the composition and vasoreactivity of extracts of MS, CC, TP… read more here.
Keywords: vasorelaxant effect; conyza canadensis; canadensis teucrium; effect ... See more keywords