Articles with "vaspin" as a keyword



Short-Term Impact of Laparoscopic Sleeve Gastrectomy on Serum Cartonectin and Vaspin Levels in Obese Subjects

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Published in 2018 at "Obesity Surgery"

DOI: 10.1007/s11695-018-3306-9

Abstract: BackgroundCartonectin is a potent anti-inflammatory adipokine that might be implicated in metabolism and energy storage. Our objective was to evaluate the influence of weight reduction following laparoscopic sleeve gastrectomy (LSG) on serum cartonectin and vaspin… read more here.

Keywords: laparoscopic sleeve; level; cartonectin; vaspin ... See more keywords

Vaspin is a novel target gene of hepatic CCAAT-enhancer-binding protein.

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Published in 2019 at "Gene"

DOI: 10.1016/j.gene.2019.144113

Abstract: Vaspin, initially identified in visceral adipose tissue, is an adipokine, and administration of recombinant vaspin leads to lowering of the endoplasmic reticulum stress which is elevated in obesity or enhancement of insulin sensitivity. CCAAT/enhancer binding… read more here.

Keywords: ccaat enhancer; enhancer binding; binding protein; vaspin novel ... See more keywords

Vaspin Alleviates Sepsis-Induced Cardiac Injury and Cardiac Inflammation by Inhibiting Kallikrein 7 in Mice

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Published in 2022 at "Mediators of Inflammation"

DOI: 10.1155/2022/1149582

Abstract: Background Vaspin is an important adipokine that is involved in cardiovascular diseases. This study is aimed at investigating whether vaspin participates in sepsis-induced cardiac injury and explored the possible mechanism. Methods First, cecal ligation and… read more here.

Keywords: cardiac injury; mice; sepsis induced; induced cardiac ... See more keywords

Vaspin Attenuates Atrial Abnormalities by Promoting ULK1/FUNDC1-Mediated Mitophagy

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Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/3187463

Abstract: The worldwide incidence and prevalence of atrial fibrillation (AF) are increasing, making it a life-threatening condition due to the higher numbers of people suffering from obesity. Vaspin, an adipokine derived from epicardial adipose tissue, has… read more here.

Keywords: atrial abnormalities; fundc1; attenuates atrial; vaspin attenuates ... See more keywords

Vaspin promotes chondrogenic differentiation of BMSCs via Akt activation in osteoarthritis

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Published in 2022 at "BMC Musculoskeletal Disorders"

DOI: 10.1186/s12891-022-05295-9

Abstract: Background The aim of this study was to investigate the role of Vaspin on the chondrogenic differentiation of bone mesenchymal stem cells (BMSCs), and its effect on chondrocyte survival and ECM secretion. We also assessed… read more here.

Keywords: differentiation; chondrogenic differentiation; vaspin; akt activation ... See more keywords

The relationship of serum vaspin level with clinical parameters in patients with fibromyalgia syndrome.

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Published in 2024 at "Cellular and molecular biology"

DOI: 10.14715/cmb/2024.70.11.6

Abstract: Vaspin plays a regulatory role in lipid and glucose metabolism and is a therapeutic adipokine against impaired glucose intolerance in obese individuals. We aimed to investigate serum vaspin levels in patients with FMS and whether… read more here.

Keywords: clinical parameters; vaspin; control group; group ... See more keywords

The effect of high-intensity interval training on serum and adipose tissues vaspin levels in rats fed a high-fat high-sucrose diet

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Published in 2022 at "Hormone Molecular Biology and Clinical Investigation"

DOI: 10.1515/hmbci-2021-0107

Abstract: Abstract Background Vaspin is an adipocytokine with insulin-sensitizing and anti-inflammatory traits. Objectives The purpose of this study was to evaluate the effect of high-intensity interval training (HIIT) on serum, visceral and subcutaneous adipose tissue vaspin… read more here.

Keywords: levels rats; effect; vaspin levels; serum ... See more keywords

Kallikrein-related peptidase 14 is the second KLK protease targeted by the serpin vaspin

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Published in 2018 at "Biological Chemistry"

DOI: 10.1515/hsz-2018-0108

Abstract: Abstract Kallikrein-related peptidases KLK5, KLK7 and KLK14 are important proteases in skin desquamation and aberrant KLK activity is associated with inflammatory skin diseases such as Netherton syndrome but also with various serious forms of cancer.… read more here.

Keywords: protease; kallikrein; second klk; kallikrein related ... See more keywords

The levels of adipokines in relation to hormonal changes during the menstrual cycle in young, normal-weight women

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Published in 2017 at "Endocrine Connections"

DOI: 10.1530/ec-17-0186

Abstract: Context The aim of this study was to assess the plasma leptin, adiponectin, resistin, visfatin/NAMPT, omentin-1, vaspin, apelin, TNF-α, IL-6 and RBP4 levels in relation to hormonal changes during the menstrual cycle in young, healthy,… read more here.

Keywords: menstrual cycle; normal weight; cycle; relation hormonal ... See more keywords

Vaspin inhibits ferroptosis: A new hope for treating myocardial ischemia–reperfusion injury

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Published in 2024 at "CytoJournal"

DOI: 10.25259/cytojournal_141_2024

Abstract: Objective: Myocardial ischemia–reperfusion injury (MIRI) is a critical pathological basis for cardiovascular diseases. In recent years, the effect of ferroptosis on MIRI has attracted extensive attention. Vaspin, an adipose tissue-derived serine protease inhibitor, has multiple… read more here.

Keywords: myocardial ischemia; ischemia reperfusion; vaspin; ferroptosis ... See more keywords

VASPIN reduces inflammation and endoplasmic reticulum stress of renal tubular epithelial cells by inhibiting HMGB1 and relieves renal ischemia-reperfusion injury.

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Published in 2020 at "European review for medical and pharmacological sciences"

DOI: 10.26355/eurrev_202009_22839

Abstract: OBJECTIVE Renal ischemia-reperfusion injury (IRI) is a clinically common issue and the resulting acute kidney injury (AKI) seriously threatens the patient's life. Therefore, prevention and treatment of renal IRI are the key to alleviating AKI… read more here.

Keywords: epithelial cells; iri; renal iri; tubular epithelial ... See more keywords