LAUSR

VAV1 Mutations Contributes to the Development of T-Cell Malignancies in Mice

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1 Published in 2019 at "Blood"

DOI: 10.1182/blood-2019-124591

Abstract: Background: VAV1 is known as an important mediator of T-cell receptor (TCR) signaling through its guanine exchange factor (GEF)-dependent and independent functions. Recent studies identified activating VAV1 mutations in several types of T-cell malignancies including… read more here.

Keywords: mice; vav1 mutants; cell; vav1 ... See more keywords