Sign Up to like & get
recommendations!
0
Published in 2017 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2017.02.027
Abstract: Abstract NADPH oxidase (NOX)‐derived reactive oxygen species (ROS) have been demonstrated to mediate the activation of NOD‐like receptor protein 3 (NLRP3) inflammasomes in podocytes in response to elevated levels of homocysteine (Hcys). However, it remains…
read more here.
Keywords:
vav2;
inflammasome activation;
hcys;
activation ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2020 at "Journal of Cell Science"
DOI: 10.1242/jcs.238337
Abstract: ABSTRACT Vav family guanine nucleotide exchange factors (GEFs) are essential regulators of immune function. Despite their structural similarity, Vav1 promotes and Vav2 opposes T cell receptor (TCR)-induced Ca2+ entry. By using a Vav1-deficient Jurkat T…
read more here.
Keywords:
vav2;
scaffolding functions;
cell activation;
vav1 ... See more keywords