Mesothelium expression of vascular cell adhesion molecule‐1 (VCAM‐1) is associated with an unfavorable prognosis in epithelial ovarian cancer (EOC)
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DOI: 10.1002/cncr.30415
Abstract: Mesothelium vascular cell adhesion molecule‐1 (VCAM‐1) expression in the metastatic epithelial ovarian cancer (EOC) microenvironment is induced by tumor and mediates tumor cell invasion. VCAM‐1 imaging suggests expression during treatment is an indicator of platinum… read more here.
Keywords: vascular cell; expression; cancer; mesothelium ... See more keywords
Cerebrovascular inflammation promotes the formation of brain metastases
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DOI: 10.1002/ijc.32902
Abstract: Brain metastases are the most prevalent intracranial malignancy. Patient outcome is poor and treatment options are limited. Hence, new avenues must be explored to identify potential therapeutic targets. Inflammation is a known critical component of… read more here.
Keywords: brain metastases; cerebrovascular inflammation; inflammation; cancer ... See more keywords
NOD2 induces VCAM-1 and ET-1 gene expression via NF-κB in human umbilical vein endothelial cells with muramyl dipeptide stimulation
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DOI: 10.1007/s00059-020-04996-y
Abstract: Objectives Endothelial dysfunction is involved in various aspects of vascular biology and different stages of cardiovascular diseases (CVDs). Nucleotide-binding oligomerization domain-containing protein (NOD) 2, a pivotal innate immune receptor for muramyl dipeptide (MDP), has been reported to… read more here.
Keywords: mdp; gene expression; expression; endothelial cells ... See more keywords
Disease-specific characteristics of vascular cell adhesion molecule-1 levels in patients with peripheral artery disease
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DOI: 10.1007/s00380-018-1315-1
Abstract: Peripheral arterial disease (PAD) is one of the most common manifestations of systemic atherosclerosis. The prevalence of unrecognized PAD is high, leading to a lack of opportunity to detect subjects at a high risk for… read more here.
Keywords: disease; cell adhesion; vascular cell; pad ... See more keywords
Serum netrin and VCAM-1 as biomarker for Egyptian patients with type IΙ diabetes mellitus
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DOI: 10.1016/j.bbrep.2021.101045
Abstract: Objective This study aimed to evaluate the serum level of netrin and soluble vascular cell adhesion molecule 1 (VCAM-I) in patients with type IΙ diabetes mellitus (T2DM) and evaluate the association of their levels with… read more here.
Keywords: patients type; netrin1 vcam1; diabetic patients; type diabetes ... See more keywords
Osteoblast-secreted WISP-1 promotes adherence of prostate cancer cells to bone via the VCAM-1/integrin α4β1 system.
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DOI: 10.1016/j.canlet.2018.03.050
Abstract: Bone metastasis is a frequent occurrence in prostate cancer (PCa) that is associated with severe complications such as fracture, bone pain and hypercalcemia. The cross-talk between metastatic cancer cells and bone is critical to the… read more here.
Keywords: pca cells; bone; cancer cells; cancer ... See more keywords
Effects of Salvia officinalis L. and Chamaemelum nobile (L.) extracts on inflammatory responses in two models of human cells: Primary subcutaneous adipocytes and neuroblastoma cell line (SK-N-SH).
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DOI: 10.1016/j.jep.2020.113614
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Salvia officinalis L. (sage), and Chamaemelum nobile (L.) (chamomile) have been used traditionally to treat various inflammatory conditions. AIMS Our study aims to investigate the anti-inflammatory properties of both plant extracts in IL-1β-stimulated… read more here.
Keywords: reduction; tnf; treatment; effect ... See more keywords
VCAM-1 Upregulation Contributes to Insensitivity of Vemurafenib in BRAF-Mutant Thyroid Cancer
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DOI: 10.1016/j.tranon.2019.10.007
Abstract: Vemurafenib, an inhibitor of mutant BRAF activity, is a promising anticancer agent for patients with BRAF-mutant metastatic melanoma. However, it is less effective in BRAF-mutant thyroid cancer, and the reason for this discrepancy is not… read more here.
Keywords: braf mutant; vcam; thyroid; thyroid cancer ... See more keywords
Detection of Vascular Reactive Oxygen Species in Experimental Atherosclerosis by High-Resolution Near-Infrared Fluorescence Imaging Using VCAM-1-Targeted Liposomes Entrapping a Fluorogenic Redox-Sensitive Probe
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DOI: 10.1155/2021/6685612
Abstract: Excessive production of reactive oxygen species (ROS) and the ensuing oxidative stress are instrumental in all phases of atherosclerosis. Despite the major achievements in understanding the regulatory pathways and molecular sources of ROS in the… read more here.
Keywords: reactive oxygen; detection; oxygen species; fluorescence ... See more keywords
VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface
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DOI: 10.1158/1078-0432.ccr-21-4011
Abstract: Abstract Purpose: Despite optimal local therapy, tumor cell invasion into normal brain parenchyma frequently results in recurrence in patients with solid tumors. The aim of this study was to determine whether microvascular inflammation can be… read more here.
Keywords: tumor brain; brain interface; brain; vcam ... See more keywords
Diagnostic Value of sST2, VCAM-1, and Adiponectin in Patients with Breast Cancer to Predict Anti-Tumour Treatment-Related Cardiac Events: A Pilot Study
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DOI: 10.1159/000525683
Abstract: Aim: The present exploratory study investigated the diagnostic value of inflammatory markers in patients with breast cancer to predict anti-tumour treatment-related cardiac events. Methods: Twenty-one patients with breast cancer were enrolled in this prospective observational… read more here.
Keywords: event; patients breast; breast cancer; vcam ... See more keywords