VCD spectroscopy reveals that a water molecule determines the conformation of azithromycin in solution.
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DOI: 10.1039/d1cc00932j
Abstract: We report the IR and VCD spectra of azithromycin, a macrolide antibiotic with a total of 18 stereogenic centers. The computational analysis of the spectra reveals that a single water molecule has to be considered… read more here.
Keywords: water molecule; conformation; vcd spectroscopy; spectroscopy ... See more keywords
VCD spectroscopy distinguishes the enamine and iminium ion of a 1,1'-binaphthyl azepine.
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DOI: 10.1039/d2cc02863h
Abstract: We present a VCD spectroscopic characterization of a chiral 1,1'-binaphthyl azepine catalyst and show that the VCD spectra of an in situ generated enamine and an ex situ prepared iminium ion are characteristically different. The… read more here.
Keywords: binaphthyl azepine; spectroscopy; vcd spectroscopy; iminium ion ... See more keywords