Abstract 1778: Preclinical characterization of the safety and antitumor activity of IMAB027-vcMMAE, an anticlaudin 6 antibody-drug conjugate
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DOI: 10.1158/1538-7445.am2018-1778
Abstract: Background Claudin 6 (CLDN6) is a tight junction membrane protein whose expression in normal tissue is confined to embryonic cells, but is aberrantly expressed in various human cancers. The anti-CLDN6 monoclonal antibody (mAb), IMAB027, has… read more here.
Keywords: imab027 vcmmae; vcmmae; cldn6; antitumor activity ... See more keywords