Novel small-molecule compound VCP979 attenuates renal fibrosis in male rats with unilateral ureteral obstruction
Sign Up to like & getrecommendations! Published in 2023 at "Experimental Biology and Medicine"
DOI: 10.1177/15353702221147569
Abstract: Renal fibrosis is a hallmark of chronic kidney disease, while efficient therapy against renal fibrosis is still lacking. In this study, we investigated the role of a novel small-molecule compound VCP979 on renal fibrosis and… read more here.
Keywords: small molecule; renal fibrosis; molecule compound; novel small ... See more keywords
A novel small molecule compound VCP979 improves ventricular remodeling in murine models of myocardial ischemia/reperfusion injury
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Medicine"
DOI: 10.3892/ijmm.2019.4413
Abstract: Persistent ventricular remodeling following myocardial ischemia/reperfusion (MI/R) injury results in functional decompensation and eventual progression to heart failure. VCP979, a novel small-molecule compound developed in-house, possesses anti-inflammatory and anti-fibrotic activities. In the present study, no… read more here.
Keywords: molecule compound; small molecule; novel small; vcp979 ... See more keywords