γδ T cells: a potent immunotherapy tool for children with high-risk acute leukemia
Sign Up to like & getrecommendations! Published in 2019 at "Cytotherapy"
DOI: 10.1016/j.jcyt.2019.03.349
Abstract: Background & Aim Leukemia is the most common cancer in childhood, accounting for almost 1 out of 3 cases. Of these malignancies, most are acute lymphoblastic leukemia (ALL), with the remaining cases largely acute myeloid… read more here.
Keywords: leukemia; potent immunotherapy; acute leukemia; vd1 ... See more keywords
Therapeutic Potential of a Novel Vitamin D3 Oxime Analogue, VD1-6, with CYP24A1 Enzyme Inhibitory Activity and Negligible Vitamin D Receptor Binding
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12070960
Abstract: The regulation of vitamin D3 actions in humans occurs mainly through the Cytochrome P450 24-hydroxylase (CYP24A1) enzyme activity. CYP24A1 hydroxylates both 25-hydroxycholecalciferol (25(OH)D3) and 1,25-dihydroxycholecalciferol (1,25(OH)2D3), which is the first step of vitamin D catabolism.… read more here.
Keywords: vitamin; inhibitory; activity; cyp24a1 ... See more keywords