Vitamin D3 cress seed mucilage -β-lactoglobulin nanocomplexes: Synthesis, characterization, encapsulation and simulated intestinal fluid in vitro release.
Sign Up to like & getrecommendations! Published in 2021 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2020.117420
Abstract: Vitamin D3 (VD3) as an essential lipid-soluble active ingredient with numerous applications in food and pharmaceutical sectors; however, poor water solubility reduces its bioavailability significantly. Application of protein-polysaccharide complexes as a promising way to protect… read more here.
Keywords: seed; cress seed; fluid; vd3 ... See more keywords
Vitamin D3 alleviates pulmonary fibrosis by regulating the MAPK pathway via targeting PSAT1 expression in vivo and in vitro.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.108212
Abstract: Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal fibrotic lung disease. However, there are insufficient drugs available for IPF treatment, and the currently used drugs are accompanied by many adverse reactions. Deficiency of vitamin… read more here.
Keywords: mapk pathway; expression; pulmonary fibrosis; psat1 ... See more keywords
Characterization of cytochrome P450 CYP109E1 from Bacillus megaterium as a novel vitamin D3 hydroxylase.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of biotechnology"
DOI: 10.1016/j.jbiotec.2016.12.023
Abstract: In this study the ability of CYP109E1 from Bacillus megaterium to metabolize vitamin D3 (VD3) was investigated. In an in vitro system using bovine adrenodoxin reductase (AdR) and adrenodoxin (Adx4-108), VD3 was converted by CYP109E1… read more here.
Keywords: vd3; cyp109e1; bacillus megaterium; cyp109e1 bacillus ... See more keywords
Redesigning CYP109E1 for Improving Catalytic Performance in 25-Hydroxyvitamin D3 Synthesis Through Synergistic Enhancement of Electron Transfer and NADPH Regeneration.
Sign Up to like & getrecommendations! Published in 2025 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.4c00879
Abstract: P450 enzymes are promising biocatalysts and play an important role in the field of drug synthesis due to their high catalytic activity and stereoselectivity. CYP109E1 from Bacillus megaterium was used to convert VD3 for the… read more here.
Keywords: synthesis; nadph regeneration; cyp109e1; vd3 ... See more keywords
Optimal serum vitamin D3 levels are associated with lower osteoarthritis risk and better overall health in US adults
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-23013-y
Abstract: To recommend serum Vitamin D3(VD3) levels for osteoarthritis patients and susceptible populations by analyzing the dose-effect relationship between VD3 and the risk of osteoarthritis(OA) and between life’s essential 8 and VD3 in OA patients. This… read more here.
Keywords: risk; serum vitamin; vd3 levels; overall health ... See more keywords
1α,25(OH)2D3(VD3) promotes Raddeanin A-induced anti-proliferative effects on HeLa cell apoptosis and autophagy through negative regulation of HPV18E6-E7/PD-L1/VDR axis
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.2005223
Abstract: ABSTRACT Raddeanin A (RA) has indicated suppressive effects on various human tumor cells, and insufficient vitamin D was associated with human papillomavirus (HPV) persistence and gynecological tumors. However, combined effects of RA and vitamin D… read more here.
Keywords: vd3; cell; hela cells; apoptosis autophagy ... See more keywords
Relative bioavailability of 25-hydroxycholecalciferol versus cholecalciferol and vitamin D3 requirements in White Pekin ducks from 15 to 42 days of age.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of animal science"
DOI: 10.1093/jas/skaf184
Abstract: This study was designed to assess the effects of varying levels of vitamin D3 (VD3) or 25-hydroxycholecalciferol (25-OH-D3) supplementary in the diet on growth performance, VD3 status, plasma calcium (Ca) levels, and tibial mineralization in… read more here.
Keywords: relative bioavailability; pekin ducks; vitamin; hydroxycholecalciferol ... See more keywords
Vitamin D protects dopaminergic neurons against neuroinflammation and oxidative stress in hemiparkinsonian rats
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-018-1266-6
Abstract: BackgroundThe deficiency in 1α, 25-dihydroxyvitamin D3 (VD3) seems to increase the risk for neurodegenerative pathologies, including Parkinson’s disease (PD). The majority of its actions are mediated by the transcription factor, VD3 receptor (VD3R).MethodsThe neuroprotective effects… read more here.
Keywords: vitamin protects; protects dopaminergic; dopaminergic neurons; stress ... See more keywords
Vitamin D_3-Loaded Nanoemulsions as a Potential Drug Delivery System for Autistic Children: Formulation Development, Safety, and Pharmacokinetic Studies
Sign Up to like & getrecommendations! Published in 2023 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-023-02501-2
Abstract: The aim of the current study is the development of a vitamin D_3 (VD3)-loaded nanoemulsion (NE) formulation to improve VD3 oral bioavailability for management of vitamin D inadequacy in autistic children. Eight NE formulations were… read more here.
Keywords: autistic children; vd3; safety; formulation ... See more keywords
Improving delivery capacity of soy 7S protein via high pressure homogenization: in the case of vitamin D3
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Food Engineering"
DOI: 10.1515/ijfe-2024-0258
Abstract: Abstract In this work, high pressure homogenization treated soy 7S protein (HPH–7S) was employed as carrier to load and delivery VD3. The encapsulation efficiency (EE) (97.88 %) and bio-accessibility (85.69 %) of VD3 was markedly improved by… read more here.
Keywords: pressure homogenization; homogenization; delivery; protein ... See more keywords
The combination of vitamin D3 and erythropoietin alleviates acute kidney injury induced by ischemia-reperfusion via inhibiting inflammation and apoptosis
Sign Up to like & getrecommendations! Published in 2021 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2020.51384.11661
Abstract: Objective(s): Acute renal ischemia may cause acute renal dysfunction due to lack of blood supply; the manifestations are renal tubular cell apoptosis, infiltration of macrophages, and microvascular destruction. Many studies have shown that erythropoietin (EPO)… read more here.
Keywords: vd3; treatment; vd3 epo; injury ... See more keywords