Articles with "vdr bound" as a keyword



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1,25(OH)2D3 Promotes Macrophage Efferocytosis Partly by Upregulating ASAP2 Transcription via the VDR-Bound Enhancer Region and ASAP2 May Affect Antiviral Immunity

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Published in 2022 at "Nutrients"

DOI: 10.3390/nu14224935

Abstract: The active form of vitamin D3, i.e., 1,25(OH)2D3, exerts an anti-inflammatory effect on the immune system, especially macrophage-mediated innate immunity. In a previous study, we identified 1,25(OH)2D3-responsive and vitamin D receptor (VDR)-bound super-enhancer regions in… read more here.

Keywords: enhancer region; vdr bound; macrophage efferocytosis; asap2 ... See more keywords