A group of novel VEGF splice variants as alternative therapeutic targets in renal cell carcinoma.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular oncology"
DOI: 10.1002/1878-0261.13401
Abstract: The efficacy of anti-angiogenic treatment by targeting VEGF/VEGF receptors in metastatic clear cell renal cell carcinoma (ccRCC) varies from patient to patient. Discovering the reasons behind this variability could lead to the identification of relevant… read more here.
Keywords: cell; renal cell; vegf; therapeutic targets ... See more keywords
Electroacupuncture reverses endothelial cell death and promotes angiogenesis through the VEGF/Notch signaling pathway after focal cerebral ischemia‐reperfusion injury
Sign Up to like & getrecommendations! Published in 2023 at "Brain and Behavior"
DOI: 10.1002/brb3.2912
Abstract: Angiogenesis is an important mechanism of recovery from ischemic stroke. Recent studies have found that there is a close relationship between the VEGF/Notch pathway and angiogenesis. It is unknown whether EA can exert a brain… read more here.
Keywords: notch signaling; signaling pathway; vegf; pathway focal ... See more keywords
Genetic determinants of circulating VEGF levels in major depressive disorder and electroconvulsive therapy response.
Sign Up to like & getrecommendations! Published in 2020 at "Drug development research"
DOI: 10.1002/ddr.21658
Abstract: Alterations in peripheral vascular endothelial growth factor (VEGF) levels were observed in major depressive disorder and relative treatments and were shown to be influenced by genetic variants. The study objective was to explore, at a… read more here.
Keywords: vegf levels; depressive disorder; vegf; major depressive ... See more keywords
Development of a mono-specific anti-VEGF bivalent nanobody with extended plasma half-life for treatment of pathologic neovascularization.
Sign Up to like & getrecommendations! Published in 2019 at "Drug testing and analysis"
DOI: 10.1002/dta.2693
Abstract: Vascular Endothelial Growth Factor (VEGF) plays a crucial role in angiogenesis within solid cancers. Thus, targeting VEGF might be part of a feasible therapy for treating pathological neovascularization, and nanobodies - derived from Heavy chain-only… read more here.
Keywords: bivalent nanobody; nanobody; half life; vegf ... See more keywords
VEGF as a modulator of the innate immune response in glioblastoma
Sign Up to like & getrecommendations! Published in 2018 at "Glia"
DOI: 10.1002/glia.23234
Abstract: VEGF is an important factor in tumor vascularization and used as target for anti‐angiogenic treatment strategies in glioma. In this study, we demonstrate for the first time that VEGF is a modulator of the innate… read more here.
Keywords: microglia macrophages; innate immune; vegf; immune response ... See more keywords
Vascular endothelial growth factor promotes transdifferentiation of astrocytes into neurons via activation of the MAPK/Erk‐Pax6 signal pathway
Sign Up to like & getrecommendations! Published in 2023 at "Glia"
DOI: 10.1002/glia.24361
Abstract: Reactive astrocytes can be transformed into new neurons. Vascular endothelial growth factor (VEGF) promotes the transformation of reactive astrocytes into neurons in ischemic brain. Therefore, in this study, the molecular mechanism of VEGF's effect on… read more here.
Keywords: vegf enhanced; vegf; mapk erk; astrocytes neurons ... See more keywords
VEGF‐A promotes angiogenesis after acute myocardial infarction through increasing ROS production and enhancing ER stress‐mediated autophagy
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28395
Abstract: Proangiogenesis is generally regarded as an effective approach for treating ischemic heart disease. Vascular endothelial growth factor (VEGF)‐A is a strong and essential proangiogenic factor. Reactive oxygen species (ROS), endoplasmic reticulum (ER) stress, and autophagy… read more here.
Keywords: lc3; production; vegf; grp78 bip ... See more keywords
Direct and indirect regulation of the tumor immune microenvironment by VEGF
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.5ru0222-082r
Abstract: Vascular endothelial growth factor‐A (VEGF) is the predominant angiogenic factor that is expressed in solid tumors. Besides its critical function in mediating tumor angiogenesis, multiple studies have demonstrated that VEGF also contributes to tumor immunosuppression.… read more here.
Keywords: microenvironment; vegf; immune cell; direct indirect ... See more keywords
Study of serum VEGF levels in patients with severe dengue infection admitted in a tertiary care hospital in Kolkata
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25529
Abstract: Dengue is the most common arboviral infection globally, but its pathogenesis is poorly explored. Vascular endothelial growth factor (VEGF) has an essential role in the host defense against viral infection. However, not much information is… read more here.
Keywords: dengue patients; vegf; infection; study ... See more keywords
Tracheal aspirate VEGF and sphingolipid metabolites in the preterm infant with later development of bronchopulmonary dysplasia
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.24022
Abstract: Vascular endothelial growth factor (VEGF) and sphingolipid metabolites, sphingosine 1‐phosphate (S1P), and ceramides are important to lung development and repair. We hypothesized specific sphingolipid and VEGF alterations would be associated with BPD development and aimed… read more here.
Keywords: vegf; vegf sphingolipid; sphingolipid metabolites; aspirate vegf ... See more keywords
Evaluating VEGF-Induced Vascular Leakage Using the Miles Assay.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-2217-9_21
Abstract: Before the endothelial mitogenic activity of the Vascular Endothelial Growth Factor A (VEGF) was described, VEGF had already been identified for its ability to induce vascular leakage. VEGF-induced vascular leakage has been most frequently studied… read more here.
Keywords: using miles; induced vascular; vegf induced; vascular leakage ... See more keywords