VEGF aptamer/i-motif-based drug co-delivery system for combined chemotherapy and photodynamic therapy.
Sign Up to like & getrecommendations! Published in 2021 at "Photodiagnosis and photodynamic therapy"
DOI: 10.1016/j.pdpdt.2021.102547
Abstract: BACKGROUND Nucleic acids used as drug delivery systems (DDS) have aroused many researchers' attention because of their high biosafety and effortless synthesis. G-quadruplex (G4) structured aptamer such as AS1411 was frequently employed to deliver photosensitizers… read more here.
Keywords: system; drug delivery; delivery; vegf aptamer ... See more keywords
VEGF aptamer/i-motif-grafted multi-functional SPION nanocarrier for chemotherapeutic/phototherapeutic synergistic research.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of biomaterials applications"
DOI: 10.1177/08853282211049620
Abstract: Chemotherapeutic agents and photosensitizers often suffer from poor tumor selectivity, high side toxicity, or low water solubility. To address these problems, various drug delivery systems (DDS) have been explored but most of them are toxic,… read more here.
Keywords: drug delivery; multi functional; chemotherapeutic phototherapeutic; vegf aptamer ... See more keywords
Two-step target recognition for the competitive inhibition activity of an anti-VEGF aptamer.
Sign Up to like & getrecommendations! Published in 2025 at "RNA"
DOI: 10.1261/rna.080524.125
Abstract: The anti-vascular endothelial growth factor (VEGF) aptamer, t44.27, is a 27-mer RNA that functions as the active component of pegaptanib, an anti-angiogenic medicine for neovascular age-related macular degeneration. The t44.27 aptamer is extensively 2'-modified and… read more here.
Keywords: aptamer; competitive inhibition; vegf aptamer; t44 ... See more keywords