Ocular Kinetics, Distribution, and Effects of Human VEGF Isoforms 121 and 165: Implications for Therapeutic Intervention.
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DOI: 10.1021/acs.molpharmaceut.5c00120
Abstract: Targeting VEGF is an established therapeutic strategy for several retinal diseases; however, gaps in understanding the kinetic behavior of VEGF in the eye hinder the interpretation of anti-VEGF pharmacokinetic/pharmacodynamic data. This study aimed to investigate… read more here.
Keywords: ocular kinetics; human vegf; vegf isoforms; elimination ... See more keywords