Anti-angiogenic effect of Interleukin-26 in oxygen-induced retinopathy mice via inhibiting NFATc1-VEGF pathway.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.04.004
Abstract: Retinal neovascularization (RNV) is a devastating pathological feature of numerous ocular diseases and is a major cause of blindness. In this study, we examined the effect and potential mechanism of interleukin-26 (IL-26) in the pathogenesis… read more here.
Keywords: oxygen induced; oxygen; rnv; induced retinopathy ... See more keywords
Association between genetic variants in the HIF1A-VEGF pathway and left ventricular regional myocardial deformation in patients with hypertrophic cardiomyopathy
Sign Up to like & getrecommendations! Published in 2020 at "Pediatric Research"
DOI: 10.1038/s41390-020-0929-z
Abstract: Background Information on genetic etiology of pediatric hypertrophic cardiomyopathy (HCM) rarely aids in risk stratification and prediction of disease onset. Little data exist on the association between genetic modifiers and phenotypic expression of myocardial performance,… read more here.
Keywords: myocardial deformation; risk; risk allele; association ... See more keywords
PIK3R5 genetic predictors of hypertension induced by VEGF-pathway inhibitors
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz239.029
Abstract: Abstract Background Hypertension is one of the major side effect of VEGF-pathway inhibitors. There are no validated biomarkers to predict which cancer patients will develop hypertension. This study aimed to identify genetic predictors of hypertension… read more here.
Keywords: predictors hypertension; pathway inhibitors; hypertension; vegf pathway ... See more keywords
Resveratrol Suppresses Tumor Progression via Inhibiting STAT3/HIF-1α/VEGF Pathway in an Orthotopic Rat Model of Non-Small-Cell Lung Cancer (NSCLC)
Sign Up to like & getrecommendations! Published in 2020 at "OncoTargets and therapy"
DOI: 10.2147/ott.s259016
Abstract: Background The STAT3/HIF-1α/VEGF pathway is associated with the development and progress of various tumors including NSCLC. The aim of the present study was to investigate whether resveratrol (RES) could suppress NSCLC progression via inhibiting the… read more here.
Keywords: hif vegf; stat3 hif; group; vegf pathway ... See more keywords
The Association of Biochemical and Genetic Biomarkers in VEGF Pathway with Depression
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14122757
Abstract: VEGF is an important neurotrophic and vascular factor involved in mental disorders. The objective of this study was to verify the effect of genetic polymorphisms in the VEGF pathway on the risk for depression, symptom… read more here.
Keywords: pathway depression; number suicide; depression; suicide attempts ... See more keywords