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   Articles with "vegf vegfr2" as a keyword



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FGF9‐induced ovarian cancer cell invasion involves VEGF‐A/VEGFR2 augmentation by virtue of ETS1 upregulation and metabolic reprogramming

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recommendations! Published in 2018 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.26820

Abstract: Ovarian cancer (OC) renders its lethality to enhanced metastasis and late detection. A plethora of growth factors including Vascular Endothelial Growth Factor (VEGF) and Fibroblast Growth Factor (FGF) stimulated signaling pathways regulate the invasive/metastatic behavior… read more here.

Keywords: vegf vegfr2; invasion; augmentation; expression ... See more keywords
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Sphingosine-1-Phosphate Receptor 1 Activity Promotes Tumor Growth by Amplifying VEGF-VEGFR2 Angiogenic Signaling

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recommendations! Published in 2019 at "Cell reports"

DOI: 10.1016/j.celrep.2019.11.036

Abstract: SUMMARY The vascular endothelial growth factor-A (VEGF-A)-VEGFR2 pathway drives tumor vascularization by activating proangiogenic signaling in endothelial cells (ECs). Here, we show that EC-sphingosine-1-phosphate receptor 1 (S1PR1) amplifies VEGFR2-mediated angiogenic signaling to enhance tumor growth.… read more here.

Keywords: tumor; vegf vegfr2; sphingosine phosphate; growth ... See more keywords

Effects of cooking oil fume derived fine particulate matter on blood vessel formation through the VEGF/VEGFR2/MEK1/2/ERK1/2/mTOR pathway in human umbilical vein endothelial cells.

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recommendations! Published in 2019 at "Environmental toxicology and pharmacology"

DOI: 10.1016/j.etap.2019.04.008

Abstract: In China, cooking oil fume derived fine particulate matter (COF-derived PM2.5) is a principal source of indoor air pollution. Here, we investigated cytotoxicity of COF-derived PM2.5, as well as the roles of VEGF, VEGFR2, MEK1/2,… read more here.

Keywords: vegf vegfr2; erk1 mtor; vegfr2 mek1; mek1 erk1 ... See more keywords
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VEGF, VEGFR2 and GSTM1 polymorphisms in outcome of multiple myeloma patients treated with thalidomide-based regimens

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recommendations! Published in 2017 at "Blood Cancer Journal"

DOI: 10.1038/bcj.2017.58

Abstract: VEGF , VEGFR2 and GSTM1 polymorphisms in outcome of multiple myeloma patients treated with thalidomide-based regimens read more here.

Keywords: polymorphisms outcome; vegfr2 gstm1; vegf vegfr2; multiple myeloma ... See more keywords
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VEGF-Independent Angiogenic Factors: Beyond VEGF/VEGFR2 Signaling

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recommendations! Published in 2022 at "Journal of Vascular Research"

DOI: 10.1159/000521584

Abstract: Tumors induce angiogenesis to acquire oxygen and nutrition from their adjacent microenvironment. Tumor angiogenesis has been believed to be induced primarily by the secretion of vascular endothelial growth factor-A (VEGF-A) from various tumors. VEGF-A binds… read more here.

Keywords: independent angiogenic; vegf vegfr2; angiogenic factors; vegf independent ... See more keywords
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Targeting VEGF-A/VEGFR2 Y949 Signaling-Mediated Vascular Permeability Alleviates Hypoxic Pulmonary Hypertension

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recommendations! Published in 2022 at "Circulation"

DOI: 10.1161/circulationaha.122.061900

Abstract: Background: Pulmonary hypertension (PH) is associated with increased expression of VEGF-A (vascular endothelial growth factor A) and its receptor, VEGFR2 (vascular endothelial growth factor 2), but whether and how activation of VEGF-A signal participates in… read more here.

Keywords: vegf vegfr2; vegfr2 y949; y949 signaling; vegfr2 ... See more keywords