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   Articles with "vegfa" as a keyword



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Exosome-mediated lncRNA SNHG11 Regulates Angiogenesis in Pancreatic Carcinoma Through miR-324-3p/VEGFA Axis.

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recommendations! Published in 2021 at "Cell biology international"

DOI: 10.1002/cbin.11703

Abstract: Pancreatic carcinoma (PC) is one of the most common and deadly human malignancies worldwide. LncRNAs play significant roles in the occurrence and development of various cancers. LncRNA SNHG11 (SNHG11) has been found to display high… read more here.

Keywords: snhg11; pancreatic carcinoma; lncrna snhg11; vegfa ... See more keywords
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Trilobatin promotes angiogenesis after cerebral ischemia–reperfusion injury via SIRT7/VEGFA signaling pathway in rats

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recommendations! Published in 2022 at "Phytotherapy Research"

DOI: 10.1002/ptr.7487

Abstract: Angiogenesis plays a pivotal role in the recovery of neurological function after ischemia stroke. Herein, we investigated the effect of trilobatin (TLB) on angiogenesis after cerebral ischemia–reperfusion injury (CIRI). The effect of TLB on angiogenesis… read more here.

Keywords: ischemia; cerebral ischemia; angiogenesis cerebral; sirt7 vegfa ... See more keywords
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Anlotinib combined with temozolomide suppresses glioblastoma growth via mediation of JAK2/STAT3 signaling pathway

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recommendations! Published in 2022 at "Cancer Chemotherapy and Pharmacology"

DOI: 10.1007/s00280-021-04380-5

Abstract: Anlotinib protects against carcinogenesis through the induction of autophagy and apoptosis. The current study evaluated the role and molecular mechanisms of anlotinib in glioblastoma, and the effects of anlotinib in combination with temozolomide (TMZ). Cell… read more here.

Keywords: vegfa; glioblastoma; growth; signaling pathway ... See more keywords
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Temporal VEGFA responsive genes in HUVECs: Gene signatures and potential ligands/receptors fine-tuning angiogenesis

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recommendations! Published in 2019 at "Journal of Cell Communication and Signaling"

DOI: 10.1007/s12079-019-00541-7

Abstract: Vascular Endothelial Growth Factor-A (VEGFA) signaling is crucial to the cellular processes involved in angiogenesis. Previously, we assembled a network of molecular reactions induced by VEGFA in human umbilical vein endothelial cell populations. Considering transcriptome… read more here.

Keywords: network; vegfa signaling; vegfa responsive; vegfa ... See more keywords
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Interferon-γ inhibits retinal neovascularization in a mouse model of ischemic retinopathy.

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recommendations! Published in 2021 at "Cytokine"

DOI: 10.1016/j.cyto.2021.155542

Abstract: Interferon-γ (IFNG) is one of the key cytokines that regulates both innate and adaptive immune responses in the body. However, the role of IFNG in the regulation of vascularization, especially in the context of Vascular… read more here.

Keywords: interferon; model; vegfa; ifng ... See more keywords
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Mechanism of dexmedetomidine regulating osteogenesis-angiogenesis coupling through the miR-361-5p/VEGFA axis in postmenopausal osteoporosis.

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recommendations! Published in 2021 at "Life sciences"

DOI: 10.1016/j.lfs.2021.119273

Abstract: AIMS Postmenopausal osteoporosis (PMOP) is a growing health problem affecting many postmenopausal women. This study intended to identify the role of dexmedetomidine (Dex) on osteoporosis (OP). MAIN METHODS Microarray analysis was performed for the gene… read more here.

Keywords: angiogenesis; dex; mir 361; osteogenesis angiogenesis ... See more keywords
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Vegfa promoter gene hypermethylation at HIF1α binding site is an early contributor to CKD progression after renal ischemia

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recommendations! Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-88000-5

Abstract: Chronic hypoxia is a major contributor to Chronic Kidney Disease (CKD) after Acute Kidney Injury (AKI). However, the temporal relation between the acute insult and maladaptive renal response to hypoxia remains unclear. In this study,… read more here.

Keywords: binding site; hif1 binding; hif1; vegfa ... See more keywords
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Functional identification of a rare vascular endothelial growth factor a (VEGFA) variant associating with the nonsyndromic cleft lip with/without cleft palate.

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recommendations! Published in 2021 at "Bioengineered"

DOI: 10.1080/21655979.2021.1912547

Abstract: Vascular endothelial growth factor A (VEGFA) is a crucial growth factor, which participates in multiple processes of human growth and development, such as angiogenesis and osteogenesis and is also necessary for development of palate. The… read more here.

Keywords: vegfa; growth factor; palate; cleft ... See more keywords
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circGLI3 Inhibits Oxidative Stress by Regulating the miR-339-5p/VEGFA Axis in IPEC-J2 Cells

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recommendations! Published in 2021 at "BioMed Research International"

DOI: 10.1155/2021/1086206

Abstract: As a new type of noncoding RNA, circular RNA (circRNA) is stable in cells and not easily degraded. This type of RNA can also competitively bind miRNAs to regulate the expression of their target genes.… read more here.

Keywords: ipec cells; mir 339; circgli3; vegfa ... See more keywords
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N-myc Downstream-Regulated Gene 1 (NDRG1) Regulates Vascular Endothelial Growth Factor A (VEGFA) and Malignancies in Glioblastoma Multiforme (GBM)

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recommendations! Published in 2022 at "BioMed Research International"

DOI: 10.1155/2022/3233004

Abstract: Background NDRG1 has been reported to exhibit relatively low expression levels in glioma tissues compared with adjacent brain tissues. Additionally, NDRG1 is reported to be a tumor suppressor with the potential to suppress the proliferation,… read more here.

Keywords: expression; endothelial growth; gbm; formation ... See more keywords
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hsa_circ_00046621 accelerates the progression of osteoarthritis via the microRNA-424-5p/VEGFA axis.

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recommendations! Published in 2022 at "Current molecular medicine"

DOI: 10.2174/1566524023666221103161203

Abstract: OBJECTIVE Circular RNAs (circRNAs) have been extensively implicated in the progression of osteoarthritis (OA). Therefore, this study explores the impact of hsa_circ_00046621 on OA progression and the related molecular mechanism. METHODS Human articular chondrocyte injury… read more here.

Keywords: mir 424; circ 0004662; hsa circ; circ ... See more keywords