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EGFR/VEGFR-2 dual inhibitor and apoptotic inducer: Design, synthesis, anticancer activity and docking study of new 2-thioxoimidazolidin-4one derivatives.

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Published in 2021 at "Life sciences"

DOI: 10.1016/j.lfs.2021.119531

Abstract: AIMS EGFR and VEGFR-2 have emerged as promising targets for cancer management as they play a crucial role in tumor growth, angiogenesis and metastasis. A novel series of 2-thioxoimidazolidin-4-one derivatives were synthesized and evaluated as… read more here.

Keywords: vegfr dual; egfr vegfr; docking study; cell ... See more keywords