Pantaloon vein grafts - an alternative fix for an old problem.
Sign Up to like & getrecommendations! Published in 2021 at "Annals of vascular surgery"
DOI: 10.1016/j.avsg.2021.01.087
Abstract: INTRODUCTION Pantaloon vein grafts (PVG) were first used to replace infrarenal aortic grafts. However, they may have other applications, such as femoral aortic bifurcation reconstruction. METHODS We herein present 2 different cases, the first with… read more here.
Keywords: pantaloon vein; femoral bifurcation; vein grafts;
A Soft, Conductive External Stent Inhibits Intimal Hyperplasia in Vein Grafts by Electroporation and Mechanical Restriction.
Sign Up to like & getrecommendations! Published in 2020 at "ACS nano"
DOI: 10.1021/acsnano.0c04827
Abstract: Intimal hyperplasia (IH) in vein grafts (VGs) is a major issue in coronary artery bypass grafting (CABG) surgery. Although external stents can attenuate IH of VGs to some extent, none of the existing external stents… read more here.
Keywords: conductive external; intimal hyperplasia; hyperplasia vein; vein grafts ... See more keywords
Saphenous vein grafts in contemporary coronary artery bypass graft surgery
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Cardiology"
DOI: 10.1038/s41569-019-0249-3
Abstract: Myocardial ischaemia resulting from obstructive coronary artery disease is a major cause of morbidity and mortality in the developed world. Coronary artery bypass graft (CABG) surgery is the gold-standard treatment in many patients with complex… read more here.
Keywords: surgery; artery; graft; coronary artery ... See more keywords
Recombinant soluble apyrase APT102 inhibits thrombosis and intimal hyperplasia in vein grafts without adversely affecting hemostasis or re‐endothelialization
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.13621
Abstract: Essentials New strategies are needed to inhibit thrombosis and intimal hyperplasia (IH) in vein grafts (VG). We studied effects of apyrase (APT102) on VGs and smooth muscle and endothelial cells (SMC/EC). APT102 inhibited thrombosis, SMC… read more here.
Keywords: apyrase apt102; intimal hyperplasia; thrombosis; vein grafts ... See more keywords
MFN2 Prevents Neointimal Hyperplasia in Vein Grafts via Destabilizing PFK1
Sign Up to like & getrecommendations! Published in 2022 at "Circulation Research"
DOI: 10.1161/circresaha.122.320846
Abstract: Background: Mechanical forces play crucial roles in neointimal hyperplasia after vein grafting; yet, our understanding of their influences on vascular smooth muscle cell (VSMC) activation remains rudimentary. Methods: A cuff mouse model was used to… read more here.
Keywords: pfk1; stretch; neointimal hyperplasia; vein grafts ... See more keywords
Pentoxifylline Prevents Restenosis by Inhibiting Cell Proliferation via p38MAPK Pathway in Rat Vein Graft Model
Sign Up to like & getrecommendations! Published in 2022 at "Cell Transplantation"
DOI: 10.1177/09636897221122999
Abstract: Coronary artery bypass grafting remains the gold standard in the therapy of advanced-stage patients. But the vein grafts are prone to restenosis or failure. Pentoxifylline (PTX) is a methylxanthine derivative with a function of inhibiting… read more here.
Keywords: cell; proliferation; restenosis; vein grafts ... See more keywords
OC26 EXTERNAL STENTING OF VEIN GRAFTS IN OFF PUMP CORONARY BYPASS SURGERY AND SEQUENTIAL GRAFTING: INTERMEDIATE RESULTS FROM A SINGLE CENTER PROSPECTIVE STUDY
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cardiovascular Medicine"
DOI: 10.2459/01.jcm.0000549907.80767.13
Abstract: Background: External stenting of vein grafts has been shown to reduce graft disease by mitigating intimal hyperplasia and improving flow pattern in on-pump single vein graft context. Aim of study is to evaluate usability and… read more here.
Keywords: vein; external stenting; stenting vein; vein grafts ... See more keywords
Microsurgical repair of neonatal iliac artery injuries with saphenous vein grafts.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of neonatal-perinatal medicine"
DOI: 10.3233/npm-181724
Abstract: Two neonates with congenital heart disease, one and thirty-one days old respectively, suffered inadvertent arterial injury from cardiac catheterization. Both insults resulted in unrecognized avulsion of the external iliac artery from its origin. The patients… read more here.
Keywords: microsurgical repair; artery; vein grafts; saphenous vein ... See more keywords
Interfering in the ALK1 Pathway Results in Macrophage-Driven Outward Remodeling of Murine Vein Grafts
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2021.784980
Abstract: Aims Vein grafts are frequently used to bypass coronary artery occlusions. Unfortunately, vein graft disease (VGD) causes impaired patency rates. ALK1 mediates signaling by TGF-β via TGFβR2 or BMP9/10 via BMPR2, which is an important… read more here.
Keywords: disease; vgd; vein grafts; alk1 signaling ... See more keywords
Reproducibility of optical coherence tomography in vein grafts used for coronary revascularization.
Sign Up to like & getrecommendations! Published in 2018 at "Cardiology journal"
DOI: 10.5603/cj.a2018.0139
Abstract: BACKGROUND Optical coherence tomography (OCT) is a high-resolution imaging modality able to provide near-histological images of vessel walls making it possible to distinguish intima and media layers of the vessel wall separately. The use of… read more here.
Keywords: coherence tomography; optical coherence; reproducibility; vein grafts ... See more keywords
Multilineage commitment of Sca-1+ cells in reshaping vein grafts
Sign Up to like & getrecommendations! Published in 2023 at "Theranostics"
DOI: 10.7150/thno.77735
Abstract: Vein graft failure remains a significant clinical problem. Similar to other vascular diseases, stenosis of vein grafts is caused by several cell lines; however, the sources of these cells remain unclear. The objective of this… read more here.
Keywords: vein grafts; sca cells; bone marrow;