Surface modified G4 PAMAM dendrimers cross the blood-brain barrier following tail-vein injections in C57BL/6J mice.
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DOI: 10.1021/acschemneuro.9b00347
Abstract: Intracranial injections are currently used to deliver drugs into the brain, as most drugs cannot cross the blood-brain barrier (BBB) following systemic injections. Moreover, multiple dosing is difficult with invasive techniques. Therefore, viable systemic techniques… read more here.
Keywords: tail vein; vein injections; brain; surface ... See more keywords