Veklury® (remdesivir) formulations inhibit initial membrane-coupled events of SARS-CoV-2 infection due to their sulfobutylether-β-cyclodextrin content.
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DOI: 10.1111/bph.16063
Abstract: BACKGROUND AND PURPOSE Despite its contradictory clinical performance, Veklury® (remdesivir) has a pivotal role in COVID-19 therapy. Possible contributions of the vehicle sulfobutylether-β-cyclodextrin (SBECD) to Veklury® effects are neglected and the powder and solution formulations… read more here.
Keywords: veklury remdesivir; infection; veklury; membrane ... See more keywords