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Published in 2022 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofac486
Abstract: Abstract Background Acute myeloid leukemia (AML) is associated with poor prognosis, particularly in elderly patients with comorbidities. Combining azacitidine (AZA) with BCL-2 inhibitor venetoclax (VEN) demonstrated significant improvement in outcomes for newly-diagnosed AML patients compared…
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Keywords:
ven aza;
myeloid leukemia;
incidence;
incidence invasive ... See more keywords
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Published in 2020 at "Blood"
DOI: 10.1182/blood-2020-138821
Abstract: Venetoclax and azacitidine (ven/aza) is our institutional preference for initial treatment of non-core binding factor AML patients age ≥60. Given potential durability of response in these patients, the role of transplant (SCT) in patients who…
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Keywords:
response;
consult;
consultancy;
ven aza ... See more keywords
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Published in 2021 at "Blood advances"
DOI: 10.1182/bloodadvances.2021005538
Abstract: Venetoclax (ven) + azacitidine (aza) is the standard of care for newly-diagnosed acute myeloid leukemia (AML) patients who are not candidates for intensive chemotherapy (IC). Some patients who are IC candidates instead receive ven/aza. We…
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Keywords:
chemotherapy;
newly diagnosed;
myeloid leukemia;
ven aza ... See more keywords
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Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.15_suppl.7011
Abstract: 7011 Background: Patients (pts) with therapy-related myeloid neoplasms (tMN), antecedent myelodysplastic syndrome, or antecedent myelodysplastic/myeloproliferative neoplasms (A-MDS/MPN) may have poor outcomes due to age and adverse genetic/karyotypic features. In the VIALE-A study, pts with tMN…
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Keywords:
chemotherapy;
ven aza;
tmn mds;
mds mpn ... See more keywords
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Published in 2022 at "Cancers"
DOI: 10.3390/cancers14082025
Abstract: Simple Summary The combination of venetoclax and azacititine (VEN–AZA) has recently been approved for the treatment of unfit newly diagnosed (ND) acute myeloid leukemia (AML) patients. Few data are available for the relapsed and/or refractory…
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Keywords:
ven aza;
aml patients;
leukemia;
group ... See more keywords