Innovative treatments for epilepsy: Venom peptides, cannabinoids, and neurostimulation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.25114
Abstract: Antiepileptic drugs have been successfully treating epilepsy and providing individuals sustained seizure freedom. However, about 30% of the patients with epilepsy present drug resistance, which means they are not responsive to the pharmacological treatment. Considering… read more here.
Keywords: venom peptides; neurostimulation; epilepsy venom; innovative treatments ... See more keywords
A connection between antimicrobial properties of venom peptides and microbial ATP synthase.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.07.146
Abstract: Venom peptides anoplin, cupiennin 1a, latarcin 1, latarcin 3a, latarcin 5, melittin, and pandinin 2 are known to have antibacterial properties. In the current study, we examined whether the antimicrobial properties of these venom peptides… read more here.
Keywords: venom peptides; atp synthase; latarcin; properties venom ... See more keywords
Using Drosophila behavioral assays to characterize terebrid venom-peptide bioactivity
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-33215-2
Abstract: The number of newly discovered peptides from the transcriptomes and proteomes of animal venom arsenals is rapidly increasing, resulting in an abundance of uncharacterized peptides. There is a pressing need for a systematic, cost effective,… read more here.
Keywords: venom peptides; bioactivity; venom; tv1 tsu1 ... See more keywords
Simulation Studies and Dynamic Interaction of Venom Peptides with Ion Channels.
Sign Up to like & getrecommendations! Published in 2018 at "Protein and peptide letters"
DOI: 10.2174/0929866525666180619095245
Abstract: BACKGROUND Arthropods such as scorpion, snake, insects, and spider as well as the marine animals like sea anemone and cone snails are venomous animals producing venoms with a complex mixture of peptide, poly peptides and… read more here.
Keywords: venom peptides; simulation studies; ion channels; peptides ion ... See more keywords
Animal venom peptides as a treasure trove for new therapeutics against neurodegenerative disorders.
Sign Up to like & getrecommendations! Published in 2018 at "Current medicinal chemistry"
DOI: 10.2174/0929867325666181031122438
Abstract: BACKGROUND Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and cerebral ischemic stroke, impose enormous socio-economic burdens on both patients and health-care systems. However, drugs targeting these diseases remain unsatisfactory, and hence there is an… read more here.
Keywords: venom peptides; animal venom; trove new; peptides treasure ... See more keywords
The Effect of Bee Venom Peptides Melittin, Tertiapin, and Apamin on the Human Erythrocytes Ghosts: A Preliminary Study
Sign Up to like & getrecommendations! Published in 2020 at "Metabolites"
DOI: 10.3390/metabo10050191
Abstract: Red blood cells (RBCs) are the most abundant cells in the human blood that have been extensively studied under morphology, ultrastructure, biochemical and molecular functions. Therefore, RBCs are excellent cell models in the study of… read more here.
Keywords: venom peptides; peptides melittin; effect; bee venom ... See more keywords
Pain-Causing Venom Peptides: Insights into Sensory Neuron Pharmacology
Sign Up to like & getrecommendations! Published in 2017 at "Toxins"
DOI: 10.3390/toxins10010015
Abstract: Venoms are produced by a wide variety of species including spiders, scorpions, reptiles, cnidarians, and fish for the purpose of harming or incapacitating predators or prey. While some venoms are of relatively simple composition, many… read more here.
Keywords: venom peptides; venom; pharmacology; pain causing ... See more keywords
Antimicrobial, Insecticidal and Cytotoxic Activity of Linear Venom Peptides from the Pseudoscorpion Chelifer cancroides.
Sign Up to like & getrecommendations! Published in 2022 at "Toxins"
DOI: 10.3390/toxins14010058
Abstract: Linear cationic venom peptides are antimicrobial peptides (AMPs) that exert their effects by damaging cell membranes. These peptides can be highly specific, and for some, a significant therapeutic value was proposed, in particular for treatment… read more here.
Keywords: cytotoxic; venom peptides; pseudoscorpion; activity ... See more keywords