Prospective Use of Brown Spider Venom Toxins as Therapeutic and Biotechnological Inputs
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2021.706704
Abstract: Brown spider (genus Loxosceles) venoms are mainly composed of protein toxins used for predation and defense. Bites of these spiders most commonly produce a local dermonecrotic lesion with gravitational spread, edema and hemorrhage, which together… read more here.
Keywords: biotechnological inputs; spider; brown spider; venom toxins ... See more keywords
An Emergent Role for Mitochondrial Bioenergetics in the Action of Snake Venom Toxins on Cancer Cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.938749
Abstract: Beyond the role of mitochondria in apoptosis initiation/execution, some mitochondrial adaptations support the metastasis and chemoresistance of cancer cells. This highlights mitochondria as a promising target for new anticancer strategies. Emergent evidence suggests that some… read more here.
Keywords: cancer; venom toxins; mitochondrial bioenergetics; snake venom ... See more keywords
Application of an Extracellular Matrix-Mimicking Fluorescent Polymer for the Detection of Proteolytic Venom Toxins
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DOI: 10.3390/toxins15040294
Abstract: The cytotoxicity caused by snake venoms is a serious medical problem that greatly contributes to the morbidity observed in snakebite patients. The cytotoxic components found in snake venoms belong to a variety of toxin classes… read more here.
Keywords: polymer; extracellular matrix; toxins application; venom toxins ... See more keywords
The deep-rooted origin of disulfide-rich spider venom toxins
Sign Up to like & getrecommendations! Published in 2023 at "eLife"
DOI: 10.7554/elife.83761
Abstract: Spider venoms are a complex concoction of enzymes, polyamines, inorganic salts, and disulfide-rich peptides (DRPs). Although DRPs are widely distributed and abundant, their bevolutionary origin has remained elusive. This knowledge gap stems from the extensive… read more here.
Keywords: venom toxins; spider venom; disulfide rich; toxin ... See more keywords