SPECT Ventilation Imaging in Asthma.
Sign Up to like & getrecommendations! Published in 2019 at "Seminars in nuclear medicine"
DOI: 10.1053/j.semnuclmed.2018.10.007
Abstract: Uneven distribution of ventilation, or ventilation heterogeneity, has been observed in asthma for over 60 years using multiple breath nitrogen washout (MBNW) studies. Ventilation heterogeneity has been known to predict airway hyperresponsiveness (the ability of… read more here.
Keywords: spect ventilation; ventilation; ventilation imaging; ventilation heterogeneity ... See more keywords
Spectral graph theory efficiently characterizes ventilation heterogeneity in lung airway networks
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the Royal Society Interface"
DOI: 10.1098/rsif.2020.0253
Abstract: This paper introduces a linear operator for the purposes of quantifying the spectral properties of transport within resistive trees, such as airflow in lung airway networks. The operator, which we call the Maury matrix, acts… read more here.
Keywords: lung airway; airway networks; ventilation; graph ... See more keywords
Small Airways Dysfunction is Associated with Increased Exacerbations in Patients with Asthma.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of applied physiology"
DOI: 10.1152/japplphysiol.00103.2022
Abstract: There is poor understanding of why some patients with asthma experience recurrent exacerbations despite high levels of treatment. We compared measurements of peripheral ventilation heterogeneity and respiratory system mechanics in participants with asthma who were… read more here.
Keywords: group; ventilation heterogeneity; dysfunction; exacerbation ... See more keywords
Ventilation heterogeneity in smokers: role of unequal lung expansion and peripheral lung structure.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of applied physiology"
DOI: 10.1152/japplphysiol.00105.2020
Abstract: Smoking-induced ventilation heterogeneity measured at the mouth via established washout indices (lung clearance index LCI and alveolar mixing efficiency AME) potentially results from unequal expansion, which can be quantified by CT, and structural changes down… read more here.
Keywords: expansion; lung expansion; unequal lung; structure ... See more keywords
Ventilation heterogeneity measured by multiple breath inert gas testing is not affected by inspired oxygen concentration in healthy humans.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of applied physiology"
DOI: 10.1152/japplphysiol.01013.2016
Abstract: Multiple breath washout (MBW) and oxygen-enhanced MRI techniques use acute exposure to 100% oxygen to measure ventilation heterogeneity. Implicit is the assumption that breathing 100% oxygen does not induce changes in ventilation heterogeneity; however, this… read more here.
Keywords: oxygen; inspired oxygen; ventilation; gas ... See more keywords
Associations between ventilation heterogeneity and physiological markers of airway calibre and gas trapping in healthy adults
Sign Up to like & getrecommendations! Published in 2017 at "European Respiratory Journal"
DOI: 10.1183/1393003.congress-2017.pa2210
Abstract: Background: Multiple breath nitrogen washout (MBNW) indices provide insight into ventilation heterogeneity globally (LCI) and within the acinar (Sacin) and conducting (Scond) airways. Normal ageing leads to an accelerated deterioration of Sacin and LCI in… read more here.
Keywords: healthy adults; airway calibre; ventilation heterogeneity; gas trapping ... See more keywords