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Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.6136
Abstract: This randomized clinical trial compares the clinical response to Gram stain–guided vs guideline-based antibiotic therapy in patients with ventilator-associated pneumonia. read more here.
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Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24814
Abstract: Acinetobacter baumannii is a pathogen responsible for nosocomial infections, especially in patients with burns and ventilator‐associated pneumonia (VAP). The aims of this study was to compare the biofilm formation capacity, antimicrobial resistance patterns and molecular… read more here.
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Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28526
Abstract: The aim of this study was to identify the association polymorphism (rs11536889) in the 3′‐untranslated region (3′‐UTR) of Toll‐like receptors 4 (TLR4) and the risk for ventilator‐associated pneumonia (VAP). miRNA database online and luciferase assays… read more here.
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Published in 2019 at "Nutrition in Clinical Practice"
DOI: 10.1002/ncp.10191
Abstract: BACKGROUND Ventilator-associated pneumonia (VAP) occurs as a life-threatening complication in critically ill mechanically ventilated patients. Probiotic administration may modify the gut microbiota; however, whether this modification could decrease VAP occurrence is not known. METHODS In… read more here.
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Published in 2021 at "Pediatric pulmonology"
DOI: 10.1002/ppul.25769
Abstract: BACKGROUND Little is known about the airway microbiome in intubated mechanically ventilated children. We sought to characterize the airway microbiome longitudinally and in association with clinical variables and possible ventilator-associated infection (VAI). METHODS Serial tracheal… read more here.
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Published in 2022 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.25816
Abstract: Pseudomonas aeruginosa is the most commonly isolated organism in tracheostomy‐dependent children with ventilator‐associated tracheobronchitis (VAT). Enteral treatment with an antipseudomonal fluoroquinolone such as ciprofloxacin or levofloxacin is sometimes employed, but supportive data are limited. The… read more here.
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Published in 2022 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.26016
Abstract: Ventilator‐associated pneumonia (VAP) is one of the most common causes of nosocomial pneumonia in ventilated neonates. Nevertheless, its diagnosis is challenging due to the nonspecific clinical parameters and the lack of sensitive biomarkers. The main… read more here.
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Published in 2021 at "Phytotherapy Research"
DOI: 10.1002/ptr.7060
Abstract: Ventilator‐associated pneumonia (VAP) resulting from bacterial infection is a prevalent medical problem in intensive care units (ICUs). The purpose of this study was to systematically review available studies on oral products employed to control and… read more here.
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Published in 2017 at "Der Anaesthesist"
DOI: 10.1007/s00101-016-0250-8
Abstract: BACKGROUND Ventilator-associated pneumonia (VAP) is one of the most common and preventable infections in mechanically ventilated patients. It is associated with a high mortality rate. To prevent VAP, various strategies address this issue using "VAP-bundles", which… read more here.
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Published in 2017 at "Intensive Care Medicine"
DOI: 10.1007/s00134-017-4858-1
Abstract: PurposeThe lateral Trendelenburg position (LTP) may hinder the primary pathophysiologic mechanism of ventilator-associated pneumonia (VAP). We investigated whether placing patients in the LTP would reduce the incidence of VAP in comparison with the semirecumbent position… read more here.
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Published in 2018 at "Intensive Care Medicine"
DOI: 10.1007/s00134-018-5154-4
Abstract: PurposeTo investigate the clinical significance of infection-related ventilator-associated complications (IVAC) and their impact on carbapenem consumption in mechanically ventilated (MV) patients colonised with extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBLE).MethodsInception cohort study from the French prospective multicenter OUTCOMEREA… read more here.