Inactivation of the Ventral Pallidum by GABAA Receptor Agonist Promotes Non-rapid Eye Movement Sleep in Rats
Sign Up to like & getrecommendations! Published in 2020 at "Neurochemical Research"
DOI: 10.1007/s11064-020-03040-z
Abstract: GABA, the most abundant inhibitory neurotransmitter in the brain, is closely linked with sleep and wakefulness. As the largest area input to the ventral pallidum (VP), the nucleus accumbens (NAc) has been confirmed to play… read more here.
Keywords: gabaa receptor; rapid eye; non rapid; receptor ... See more keywords
Histamine Excites Rat GABAergic Ventral Pallidum Neurons via Co-activation of H1 and H2 Receptors
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Bulletin"
DOI: 10.1007/s12264-018-0277-8
Abstract: The ventral pallidum (VP) is a crucial component of the limbic loop of the basal ganglia and participates in the regulation of reward, motivation, and emotion. Although the VP receives afferent inputs from the central… read more here.
Keywords: histaminergic system; central histaminergic; histamine excites; ventral pallidum ... See more keywords
Projections from D2 Neurons in Different Subregions of Nucleus Accumbens Shell to Ventral Pallidum Play Distinct Roles in Reward and Aversion.
Sign Up to like & getrecommendations! Published in 2021 at "Neuroscience bulletin"
DOI: 10.1007/s12264-021-00632-9
Abstract: The nucleus accumbens shell (NAcSh) plays an important role in reward and aversion. Traditionally, NAc dopamine receptor 2-expressing (D2) neurons are assumed to function in aversion. However, this has been challenged by recent reports which… read more here.
Keywords: accumbens shell; aversion; projections neurons; reward aversion ... See more keywords
Chronic chemogenetic manipulation of ventral pallidum targeted neurons in male rats fed an obesogenic diet
Sign Up to like & getrecommendations! Published in 2022 at "Brain Research"
DOI: 10.1016/j.brainres.2022.147886
Abstract: Current treatments for obesity do not reliably reduce body weight over time. New interventional strategies, including chemogenetics, carry promise based on preclinical animal studies. Here, we focused on the ventral pallidum (VP) due to its… read more here.
Keywords: targeted neurons; ventral pallidum; obesogenic diet; chemogenetic manipulation ... See more keywords
Opposing Regulation of Cocaine Seeking by Glutamate and GABA Neurons in the Ventral Pallidum
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.01.023
Abstract: SUMMARY Projections from the nucleus accumbens to the ventral pallidum (VP) regulate relapse in animal models of addiction. The VP contains GABAergic (VPGABA) and glutamatergic (VPGlu) neurons, and a subpopulation of GABAergic neurons co-express enkephalin… read more here.
Keywords: vpgaba; cocaine seeking; cocaine; vpglu neurons ... See more keywords
Songbird Ventral Pallidum Sends Diverse Performance Error Signals to Dopaminergic Midbrain
Sign Up to like & getrecommendations! Published in 2019 at "Neuron"
DOI: 10.1016/j.neuron.2019.04.038
Abstract: Motor skills improve with practice, requiring outcomes to be evaluated against ever-changing performance benchmarks, yet it remains unclear how performance error signals are computed. Here, we show that the songbird ventral pallidum (VP) is required… read more here.
Keywords: songbird ventral; error signals; performance; performance error ... See more keywords
Ventral pallidum is essential for cocaine relapse after voluntary abstinence in rats
Sign Up to like & getrecommendations! Published in 2019 at "Neuropsychopharmacology"
DOI: 10.1038/s41386-019-0507-4
Abstract: Addiction is a chronic relapsing disorder, and during recovery many people experience several relapse events as they attempt to voluntarily abstain from drug. New preclinical relapse models have emerged that capture this common human experience,… read more here.
Keywords: relapse; drug; abstinence; voluntary abstinence ... See more keywords
Histamine and its H1 receptors in the ventral pallidum mediate formalin-induced pain-related behaviors through this region and spinal cord opioid receptors.
Sign Up to like & getrecommendations! Published in 2023 at "Behavioural pharmacology"
DOI: 10.1097/fbp.0000000000000724
Abstract: Many structures of the central nervous system recruit different neurotransmitters in pain processing. This study focused on the contribution of histamine and its H1 receptors in the ventral pallidum (VP) in mediating pain-triggered behaviors. Intra-VP… read more here.
Keywords: ventral pallidum; histamine receptors; opioid receptors; receptors ventral ... See more keywords
The ventral pallidum and relapse in alcohol seeking
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DOI: 10.1111/bph.15160
Abstract: Alcohol‐use disorders are chronically relapsing conditions characterized by cycles of use, abstinence and relapse. The ventral pallidum (VP) is a key node in the neural circuits controlling relapse to alcohol seeking and a key target… read more here.
Keywords: relapse alcohol; relapse; alcohol seeking; alcohol ... See more keywords
Recruitment and disruption of ventral pallidal cue encoding during alcohol seeking
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Neuroscience"
DOI: 10.1111/ejn.14527
Abstract: A critical area of inquiry in the neurobiology of alcohol abuse is the mechanism by which cues gain the ability to elicit alcohol use. Previously, we found that cue‐evoked activity in rat ventral pallidum robustly… read more here.
Keywords: cues trained; cue; ventral pallidal; sucrose cues ... See more keywords
Activity of a direct VTA to ventral pallidum GABA pathway encodes unconditioned reward value and sustains motivation for reward
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abm5217
Abstract: Dopamine signaling from the ventral tegmental area (VTA) plays critical roles in reward-related behaviors, but less is known about the functions of neighboring VTA GABAergic neurons. We show here that a primary target of VTA… read more here.
Keywords: reward value; vta; ventral pallidum; reward ... See more keywords