Transgenic human embryonic stem cells overexpressing FGF2 stimulate neuroprotection following spinal cord ventral root avulsion
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DOI: 10.1016/j.expneurol.2017.04.009
Abstract: &NA; Ventral root avulsion (VRA) triggers a strong glial reaction which contributes to neuronal loss, as well as to synaptic detachment. To overcome the degenerative effects of VRA, treatments with neurotrophic factors and stem cells… read more here.
Keywords: root avulsion; overexpressing fgf2; ventral root; embryonic stem ... See more keywords
Inverse modulation of motor neuron cellular and synaptic properties can maintain the same motor output
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2017.07.047
Abstract: Although often examined in isolation, a single neuromodulator typically has multiple cellular and synaptic effects. Here, we have examined the interaction of the cellular and synaptic effects of 5-HT in the lamprey spinal cord. 5-HT… read more here.
Keywords: cellular synaptic; motor output; motor neuron; ventral root ... See more keywords