Amotivation is associated with smaller ventral striatum volumes in older patients with schizophrenia
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Geriatric Psychiatry"
DOI: 10.1002/gps.4818
Abstract: Motivational deficits are prevalent in patients with schizophrenia, persist despite antipsychotic treatment, and predict long‐term outcomes. Evidence suggests that patients with greater amotivation have smaller ventral striatum (VS) volumes. We wished to replicate this finding… read more here.
Keywords: striatum volumes; ventral striatum; patients schizophrenia; smaller ventral ... See more keywords
Nigrostriatal and mesolimbic control of sleep–wake behavior in rat
Sign Up to like & getrecommendations! Published in 2019 at "Brain Structure and Function"
DOI: 10.1007/s00429-019-01921-w
Abstract: The midbrain dopamine system via the dorsal and ventral striatum regulates a wide range of behaviors. To dissect the role of dopaminergic projections to the dorsal striatum (nigrostriatal projection) and ventral striatum (mesolimbic projection) in… read more here.
Keywords: sleep wake; wake behavior; ventral striatum; nigrostriatal mesolimbic ... See more keywords
DRD2 Genotype-Based Variants Modulates D2 Receptor Distribution in Ventral Striatum
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Neurobiology"
DOI: 10.1007/s12035-019-1543-0
Abstract: Dopaminergic signaling within the striatum is crucial for motor planning and mental function. Neurons within the striatum contain two dopamine D2 receptor isoforms—D2 long and D2 short. The amount of expression for these receptor isoforms… read more here.
Keywords: ventral striatum; drd2 genotype; striatum; genotype ... See more keywords
Dopamine genetic risk is related to food addiction and body mass through reduced reward-related ventral striatum activity
Sign Up to like & getrecommendations! Published in 2019 at "Appetite"
DOI: 10.1016/j.appet.2018.09.010
Abstract: The prevalence rate of obesity continues to rise in the U.S., but effective treatment options remain elusive resulting in increased emphasis on prevention. One such area of prevention research capitalizes on the relatively novel behavioral… read more here.
Keywords: food addiction; ventral striatum; food; striatum activity ... See more keywords
Chronic methylphenidate preferentially alters catecholamine protein targets in the parietal cortex and ventral striatum
Sign Up to like & getrecommendations! Published in 2019 at "Neurochemistry International"
DOI: 10.1016/j.neuint.2019.01.016
Abstract: ABSTRACT The psychostimulant methylphenidate (MPH) is the primary drug treatment for attention deficit hyperactivity disorder (ADHD) in children. MPH is well known to acutely block the dopamine (DAT) and noradrenaline (NET) transporters. Its effect on… read more here.
Keywords: parietal cortex; ventral striatum; mph; treatment ... See more keywords
Brain networks of social action-outcome contingency: The role of the ventral striatum in integrating signals from the sensory cortex and medial prefrontal cortex
Sign Up to like & getrecommendations! Published in 2017 at "Neuroscience Research"
DOI: 10.1016/j.neures.2017.04.015
Abstract: Social interactions can be facilitated by action-outcome contingency, in which self-actions result in relevant responses from others. Research has indicated that the striatal reward system plays a role in generating action-outcome contingency signals. However, the… read more here.
Keywords: outcome contingency; ventral striatum; contingency; action outcome ... See more keywords
Heightened connectivity between the ventral striatum and medial prefrontal cortex as a biomarker for stress-related psychopathology: understanding interactive effects of early and more recent stress
Sign Up to like & getrecommendations! Published in 2017 at "Psychological Medicine"
DOI: 10.1017/s0033291717003348
Abstract: Background The experience of childhood maltreatment is a significant risk factor for the development of depression. This risk is particularly heightened after exposure to additional, more contemporaneous stress. While behavioral evidence exists for this relation,… read more here.
Keywords: symptomatology; ventral striatum; connectivity; exposure ... See more keywords
Ventral Striatum Lesions Do Not Affect Reinforcement Learning With Deterministic Outcomes on Slow Time Scales
Sign Up to like & getrecommendations! Published in 2017 at "Behavioral Neuroscience"
DOI: 10.1037/bne0000211
Abstract: A large body of work has implicated the ventral striatum (VS) in aspects of reinforcement learning (RL). However, less work has directly examined the effects of lesions in the VS, or other forms of inactivation,… read more here.
Keywords: ventral striatum; striatum lesions; reinforcement learning; working memory ... See more keywords
The motivational role of the ventral striatum and amygdala in learning from gains and losses.
Sign Up to like & getrecommendations! Published in 2023 at "Behavioral neuroscience"
DOI: 10.1037/bne0000558
Abstract: The ventral striatum (VS) and amygdala are two structures often implicated as essential structures for learning. The literature addressing the contribution of these areas to learning, however, is not entirely consistent. We propose that these… read more here.
Keywords: learning gains; gains losses; ventral striatum; striatum amygdala ... See more keywords
Offline ventral subiculum-ventral striatum serial communication is required for spatial memory consolidation
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-13703-3
Abstract: The hippocampal formation is considered essential for spatial navigation. In particular, subicular projections have been suggested to carry spatial information from the hippocampus to the ventral striatum. However, possible cross-structural communication between these two brain… read more here.
Keywords: memory consolidation; ventral striatum; striatum; subiculum ventral ... See more keywords
Friendship stability in adolescence is associated with ventral striatum responses to vicarious rewards
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-020-20042-1
Abstract: An important task for adolescents is to form and maintain friendships. In this three-wave biannual study, we used a longitudinal neuroscience perspective to examine the dynamics of friendship stability. Relative to childhood and adulthood, adolescence… read more here.
Keywords: ventral striatum; friendship stability; adolescence; striatum ... See more keywords