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Published in 2020 at "Psychopharmacology"
DOI: 10.1007/s00213-020-05697-4
Abstract: RATIONALE It has been reported that patients with major depressive disorder (MDD) are prone to developing ventricular arrhythmias. Moreover, the Sigma-1 receptor not only plays a crucial role in MDD but has also been shown… read more here.
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Published in 2020 at "Heart rhythm"
DOI: 10.1016/j.hrthm.2019.12.022
Abstract: BACKGROUND Dispersion in ventricular repolarization is relevant for arrhythmogenesis. OBJECTIVE To determine the spatiotemporal effects of sympathetic stimulation on ventricular repolarization. METHODS In five anesthetized female open chested pigs ventricular repolarization was measured from the… read more here.
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Published in 2021 at "Journal of electrocardiology"
DOI: 10.1016/j.jelectrocard.2021.08.020
Abstract: BACKGROUND Because of cardiac hypertrophy and electrophysiological alterations associated with preeclampsia, worsening of preexisting arrhythmias or occurrence of de novo arrhythmias are common in patients with preeclampsia. Tp-e/QT and Tpe/QTc ratios are accepted as reliable… read more here.
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Published in 2023 at "SLEEP"
DOI: 10.1093/sleep/zsad077.0441
Abstract: Obstructive sleep apnea (OSA) is associated with prolonged ventricular repolarization at baseline that further increases during sleep when an apnea/hypopnea event occurs. Aggressive treatment of OSA with positive airway pressure therapy (PAP) may further prolong… read more here.
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Published in 2019 at "Annals of Noninvasive Electrocardiology"
DOI: 10.1111/anec.12713
Abstract: The duration of ventricular repolarization (VR) and its spatial and temporal heterogeneity are central elements in arrhythmogenesis. We studied the adaptation of VR duration and dispersion and their relationship in healthy human subjects during atrial… read more here.
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Published in 2019 at "Annals of Noninvasive Electrocardiology"
DOI: 10.1111/anec.12734
Abstract: We investigated the role of ventricular repolarization parameters to predict complete atrioventricular block in patients undergoing transcatheter aortic valve implantation (TAVI). read more here.
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Published in 2021 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.15013
Abstract: Aims Hydroxychloroquine has been suggested as possible treatment for severe acute respiratory syndrome‐coronavirus‐2. Studies reported an increased risk of QTcF‐prolongation after treatment with hydroxychloroquine. The aim of this study was to analyse the concentration‐dependent effects… read more here.
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Published in 2019 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2019-0286
Abstract: Several studies have reported that high doses of synthetic anabolic androgenic steroids (AAS) can have serious negative effects on health, including the cardiovascular system. The aim of this study was to evaluate the combined effects… read more here.
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Published in 2019 at "Circulation Research"
DOI: 10.1161/res.125.suppl_1.102
Abstract: Introduction: Sudden cardiac death (SCD) is the leading cause of death in USA. Heart failure (HF) confers high SCD risk, but most SCD victims do not have HF or well-defined genetic abnormalities. The underlying mechanisms… read more here.
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Published in 2022 at "Caspian Journal of Internal Medicine"
DOI: 10.22088/cjim.13.3.533
Abstract: Background: Ventricular repolarization measurement by QTc interval and QT dispersion can recognize high-risk patients. Previous research tended to evaluate the act of repolarization indicators alone but this study aimed to elucidate their prognostic utility before… read more here.
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Published in 2019 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2019.00916
Abstract: Background and Objectives: Enhanced beat-to-beat variability of ventricular repolarization (BVR) has been linked to arrhythmias and sudden cardiac death. Recent experimental studies on human left ventricular epicardial electrograms have shown that BVR closely interacts with… read more here.