Sigma-1 receptor ligands improves ventricular repolarization-related ion remodeling in rats with major depression disorder.
Sign Up to like & getrecommendations! Published in 2020 at "Psychopharmacology"
DOI: 10.1007/s00213-020-05697-4
Abstract: RATIONALE It has been reported that patients with major depressive disorder (MDD) are prone to developing ventricular arrhythmias. Moreover, the Sigma-1 receptor not only plays a crucial role in MDD but has also been shown… read more here.
Keywords: depression; repolarization related; ica; sigma receptor ... See more keywords
Stellate ganglion stimulation causes spatiotemporal changes of ventricular repolarization in pig.
Sign Up to like & getrecommendations! Published in 2020 at "Heart rhythm"
DOI: 10.1016/j.hrthm.2019.12.022
Abstract: BACKGROUND Dispersion in ventricular repolarization is relevant for arrhythmogenesis. OBJECTIVE To determine the spatiotemporal effects of sympathetic stimulation on ventricular repolarization. METHODS In five anesthetized female open chested pigs ventricular repolarization was measured from the… read more here.
Keywords: stimulation; repolarization; lsgs; ventricular repolarization ... See more keywords
Impact of preeclampsia on ventricular repolarization indices.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of electrocardiology"
DOI: 10.1016/j.jelectrocard.2021.08.020
Abstract: BACKGROUND Because of cardiac hypertrophy and electrophysiological alterations associated with preeclampsia, worsening of preexisting arrhythmias or occurrence of de novo arrhythmias are common in patients with preeclampsia. Tp-e/QT and Tpe/QTc ratios are accepted as reliable… read more here.
Keywords: repolarization indices; preeclampsia; ventricular repolarization; impact preeclampsia ... See more keywords
0441 Positive airway pressure therapy associated changes in ventricular repolarization in patients with heart failure
Sign Up to like & getrecommendations! Published in 2023 at "SLEEP"
DOI: 10.1093/sleep/zsad077.0441
Abstract: Obstructive sleep apnea (OSA) is associated with prolonged ventricular repolarization at baseline that further increases during sleep when an apnea/hypopnea event occurs. Aggressive treatment of OSA with positive airway pressure therapy (PAP) may further prolong… read more here.
Keywords: patients heart; ventricular repolarization; pap; failure ... See more keywords
Adaptation of ventricular repolarization duration and dispersion during changes in heart rate induced by atrial stimulation
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Noninvasive Electrocardiology"
DOI: 10.1111/anec.12713
Abstract: The duration of ventricular repolarization (VR) and its spatial and temporal heterogeneity are central elements in arrhythmogenesis. We studied the adaptation of VR duration and dispersion and their relationship in healthy human subjects during atrial… read more here.
Keywords: adaptation; ventricular repolarization; duration dispersion; duration ... See more keywords
Predictive role of ventricular repolarization parameters for the occurrence of complete heart block in patients undergoing transcatheter aortic valve implantation
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Noninvasive Electrocardiology"
DOI: 10.1111/anec.12734
Abstract: We investigated the role of ventricular repolarization parameters to predict complete atrioventricular block in patients undergoing transcatheter aortic valve implantation (TAVI). read more here.
Keywords: undergoing transcatheter; repolarization parameters; role ventricular; patients undergoing ... See more keywords
Effect of hydroxychloroquine on the cardiac ventricular repolarization: A randomized clinical trial
Sign Up to like & getrecommendations! Published in 2021 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.15013
Abstract: Aims Hydroxychloroquine has been suggested as possible treatment for severe acute respiratory syndrome‐coronavirus‐2. Studies reported an increased risk of QTcF‐prolongation after treatment with hydroxychloroquine. The aim of this study was to analyse the concentration‐dependent effects… read more here.
Keywords: hydroxychloroquine; wave morphology; effect; morphology ... See more keywords
Combined effects of exercise training and high doses of anabolic steroids on cardiac autonomic modulation and ventricular repolarization properties in rats.
Sign Up to like & getrecommendations! Published in 2019 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2019-0286
Abstract: Several studies have reported that high doses of synthetic anabolic androgenic steroids (AAS) can have serious negative effects on health, including the cardiovascular system. The aim of this study was to evaluate the combined effects… read more here.
Keywords: cardiac autonomic; exercise training; repolarization; autonomic modulation ... See more keywords
Beat-to-beat cardiac repolarization lability increases during hypoxemia and arousals in obstructive sleep apnea patients
Sign Up to like & getrecommendations! Published in 2024 at "American Journal of Physiology - Heart and Circulatory Physiology"
DOI: 10.1152/ajpheart.00760.2023
Abstract: Obstructive sleep apnea (OSA) is associated with the progression of cardiovascular diseases, arrhythmias, and sudden cardiac death (SCD). However, the acute impacts of OSA and its consequences on heart function are not yet fully elucidated.… read more here.
Keywords: accompanying arousals; repolarization lability; physiology; repolarization ... See more keywords
Abstract 102: Molecular, Cellular and Systemic Mechanism of Nonlinear Dynamic Patterns of Ventricular Repolarization and Spontaneous Arrhythmic Sudden Death in Non-ischemic Heart Failure
Sign Up to like & getrecommendations! Published in 2019 at "Circulation Research"
DOI: 10.1161/res.125.suppl_1.102
Abstract: Introduction: Sudden cardiac death (SCD) is the leading cause of death in USA. Heart failure (HF) confers high SCD risk, but most SCD victims do not have HF or well-defined genetic abnormalities. The underlying mechanisms… read more here.
Keywords: death; spontaneous arrhythmic; repolarization; heart failure ... See more keywords
Empagliflozin’s role in reducing ventricular repolarization heterogeneity: insights into cardiovascular mortality decline from the EMPATHY-HEART trial
Sign Up to like & getrecommendations! Published in 2024 at "Cardiovascular Diabetology"
DOI: 10.1186/s12933-024-02311-1
Abstract: The incidence of myocardial infarction (MI) and sudden cardiac death (SCD) is significantly higher in individuals with Type 2 Diabetes Mellitus (T2DM) than in the general population. Strategies for the prevention of fatal arrhythmias are… read more here.
Keywords: ventricular repolarization; heart; twh; cardiovascular mortality ... See more keywords