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Published in 2017 at "Journal of Clinical Neuroscience"
DOI: 10.1016/j.jocn.2017.04.010
Abstract: Rostral ventrolateral medulla (RVLM) plays an essential role in blood pressure homeostasis. This study was aimed to investigate the mechanism of neuronal activity and synaptic transmission in the RVLM. Medulla oblongata slices were carefully obtained… read more here.
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Published in 2017 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2017.07.039
Abstract: Activation of the serotonin type 4 (5-HT4) receptors has been reported to improve abdominal pain in patients with functional gastrointestinal disorders and reduce visceral nociception in animal models. Earlier studies have proposed that 5-HT4 agonist… read more here.
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Published in 2018 at "Hypertension Research"
DOI: 10.1038/s41440-018-0105-6
Abstract: The rostral ventrolateral medulla (RVLM) plays a key role in mediating the development of stress-induced hypertension (SIH) by excitation and/or inhibition of sympathetic preganglionic neurons. The voltage-gated sodium channel Nav1.6 has been found to contribute… read more here.
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Published in 2022 at "Clinical and Experimental Hypertension"
DOI: 10.1080/10641963.2021.2007942
Abstract: ABSTRACT Background The rostral ventrolateral medulla (RVLM) plays a key role in mediating the development of stress-induced hypertension (SIH). Furthermore, enhanced glutamate transport within glutamatergic neurons in the RVLM mediates pressor responses. Data from our… read more here.
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Published in 2018 at "SHOCK"
DOI: 10.1097/shk.0000000000001011
Abstract: ABSTRACT Decompensation, a critical phase in the response to hemorrhage, is characterized by profound sympathoinhibition and the overriding of baroreflex mediated compensation. As sympathoexcitatory neurons of the rostral ventrolateral medulla (RVLM) maintain vasomotor tone and… read more here.
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Published in 2017 at "Neural Plasticity"
DOI: 10.1155/2017/3256325
Abstract: It has been demonstrated that homocysteine (HCY) is a significant risk factor of hypertension, which is characterized by overactivity of sympathetic tone. Excessive oxidative stress in the rostral ventrolateral medulla (RVLM), a key region for… read more here.
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Published in 2017 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-017-0942-2
Abstract: BackgroundNeuroinflammation plays hypertensive roles in the uninjured autonomic nuclei of the central nervous system, while its mechanisms remain unclear. The present study is to investigate the effect of neuroinflammation on autophagy in the neurons of… read more here.
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Published in 2017 at "Frontiers in Neural Circuits"
DOI: 10.3389/fncir.2017.00009
Abstract: Spinally projecting neurons in the rostral ventrolateral medulla (RVLM) play a critical role in the generation of vasomotor sympathetic tone and are thought to receive convergent input from neurons at every level of the neuraxis;… read more here.
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Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.756542
Abstract: A sedentary lifestyle is the top preventable cause of death and accounts for substantial socioeconomic costs to society. The rostral ventrolateral medulla regulates blood pressure under normal and pathophysiological states, and demonstrates inactivity-related structural and… read more here.
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Published in 2019 at "Arquivos Brasileiros de Cardiologia"
DOI: 10.5935/abc.20190166
Abstract: Background Arterial hypertension is a precursor to the development of heart and renal failure, furthermore is associated with elevated oxidative markers. Environmental enrichment of rodents increases performance in memory tasks, also appears to exert an… read more here.