Overexpression of BDNF in the ventrolateral periaqueductal gray regulates the behavior of epilepsy–migraine comorbid rats
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2594
Abstract: To investigate the effects of brain‐derived neurotrophic factor (BDNF) overexpression in the ventrolateral periaqueductal gray (vlPAG) on behavioral changes in epilepsy–migraine comorbid rats. read more here.
Keywords: periaqueductal gray; comorbid rats; epilepsy migraine; ventrolateral periaqueductal ... See more keywords
Sex‐specific cannabinoid 1 receptors on GABAergic neurons in the ventrolateral periaqueductal gray mediate analgesia in mice
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25334
Abstract: Sex differences in analgesic effects have gradually attracted public attention in preclinical and clinical studies. Both human and animal females are more sensitive to cannabinoid antinociception than males. Expression of the cannabinoid 1 receptor (CB1R)… read more here.
Keywords: periaqueductal gray; cb1rs vlpag; ventrolateral periaqueductal; sex ... See more keywords
Activation orexin 1 receptors in the ventrolateral periaqueductal gray matter attenuate nitroglycerin-induced migraine attacks and calcitonin gene related peptide up-regulation in trigeminal nucleus caudalis of rats
Sign Up to like & getrecommendations! Published in 2020 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2020.107981
Abstract: This study aims to explore whether orexin 1 receptors (Orx1R) in the ventrolateral periaqueductal gray matter (vlPAG) play a role in the modulation of migraine headaches in adult male Wistar rats. To model chronic migraine-associated… read more here.
Keywords: orexin receptors; ventrolateral periaqueductal; gray matter; periaqueductal gray ... See more keywords
Differential sensitivity of presynaptic and postsynaptic GABAB receptors in rat ventrolateral periaqueductal gray
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DOI: 10.1097/wnr.0000000000000906
Abstract: The ventrolateral periaqueductal gray (PAG) in the midbrain plays a key role in the descending pain modulatory system. &ggr;-Aminobutyric acid type B (GABAB) receptors belong to a metabotropic receptor subfamily and mediate both presynaptic and… read more here.
Keywords: gabab; ventrolateral periaqueductal; presynaptic postsynaptic; postsynaptic gabab ... See more keywords