Hindbrain estrogen receptor regulation of ventromedial hypothalamic glycogen metabolism and glucoregulatory transmitter expression in the hypoglycemic male rat
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2019.03.053
Abstract: Estrogen receptor-alpha (ERα) and -beta (ERβ) occur in key elements of the brain gluco-homeostatic network in both sexes, including the hindbrain dorsal vagal complex (DVC), but the influence of distinct receptor populations on this critical… read more here.
Keywords: glycogen metabolism; glycogen; male; receptor ... See more keywords
Systemic Glucoregulation by Glucose-Sensing Neurons in the Ventromedial Hypothalamic Nucleus (VMH)
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the Endocrine Society"
DOI: 10.1210/js.2016-1104
Abstract: The ventromedial hypothalamic nucleus (VMH) regulates glucose production in the liver as well as glucose uptake and utilization in peripheral tissues, including skeletal muscle and brown adipose tissue, via efferent sympathetic innervation and neuroendocrine mechanisms.… read more here.
Keywords: vmh; glucose sensing; ventromedial hypothalamic; nucleus vmh ... See more keywords
Inhibition of glycogen phosphorylase stimulates ventromedial hypothalamic nucleus AMP‐activated protein kinase
Sign Up to like & getrecommendations! Published in 2017 at "Physiological Reports"
DOI: 10.14814/phy2.13484
Abstract: The glucose polymer glycogen is a vital fuel reserve in the brain. The mediobasal hypothalamic energy sensor AMP‐activated protein kinase (AMPK) maintains glucostasis via neurotransmitter mechanisms that suppress [γ‐aminobutyric acid; GABA] or stimulate [nitric oxide;… read more here.
Keywords: glycogen; activated protein; protein kinase; ventromedial hypothalamic ... See more keywords
Effects of Ventromedial Hypothalamic Nucleus (VMN) Aromatase Gene Knockdown on VMN Glycogen Metabolism and Glucoregulatory Neurotransmission
Sign Up to like & getrecommendations! Published in 2023 at "Biology"
DOI: 10.3390/biology12020242
Abstract: Simple Summary The brain is a target for steroid hormones derived from the circulation or synthesized locally. Central estrogen receptors control neural functions that preserve whole-body energy stability and optimize blood levels of glucose, a… read more here.
Keywords: aromatase; vmn; hypothalamic nucleus; gene ... See more keywords
Norepinephrine Regulation of Ventromedial Hypothalamic Nucleus Metabolic-Sensory Neuron 5′-AMP-Activated Protein Kinase Activity: Impact of Estradiol
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21062013
Abstract: The mediobasal hypothalamus (MBH) shapes the neural regulation of glucostasis by 5′-AMP-activated protein kinase (AMPK)-dependent mechanisms. Yet, the neurochemical identity and neuroanatomical distribution of MBH neurons that express glucoprivic-sensitive AMPK remain unclear. The neurotransmitters γ-aminobutyric… read more here.
Keywords: activated protein; protein kinase; ventromedial hypothalamic; hypothalamic nucleus ... See more keywords